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流行性出血热病毒感染乳小白鼠的病理组织学与病毒抗原定位研究

Observaoon of Pathological and Viral Antigen of Epidemic Hemorrhagic Fever Virus Infection in Suckling Mice
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摘要 流行性出血热病毒感染乳小白鼠的病理组织学与病毒抗原定位研究郭广松,肖红,程丽,文莉,杨占秋(湖北医科大学病理学教研室,武汉430071)(湖北医科大学病毒研究所,武汉430071)关键词病毒抗原,流行性出血热,乳小白鼠,病理变化Huggirls(19... pidemic hemorrhagic fever virus origined from patients with epidemic hemorrhagic fever was inoculated into suckling mice,The results showed that the suckling mice died regularly,The viral antigenand pathological damage appeared in the brain,lung,liver and kidney,The characterization of patho-logical changes were congestion, hemorrhage and degeneration of blood vessels.The viral perticles canbe found in hippocampus region,The viral antigen can be detected in cytoplasm.The resultS suggestthat suckling mice were susceptible for human original epidemic hemorrhagic fever virus.
出处 《中国病毒学》 CSCD 1994年第1期81-83,共3页 Virologica Sinica
关键词 病毒抗原 流行性出血热 病理 Virai antigen,Epidetmc hemorrtiagic fever,Suckling mice,Pathological damage
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