胃癌的容量校正有丝分裂指数与预后

ENGLISH ABSTRACTS OF ORIGINAL ARTICLES Volume-Corrected Mitotic index as Prognostic Indicator in Human Gastric Cancer

对５５例胃癌术后病人，按Ｈａａｐａｓａｌｏ的方法进行容量校正有丝分裂指数（Ｍ／Ｖ指数）测定。本文就Ｍ／Ｖ指数、临床分期、病理分型与平均生存期五年累积生存率的相关关系进行了分析。结果发现Ｍ／Ｖ指数和临床分期与生存率有密切关系，而病理分型则无统计学意义。另就一、二、四年生存率来看，Ｍ／Ｖ指数是判断预后的最佳指标，Ｍ／Ｖ指数＞３０者，二年内无死亡．９０％的病人生存期超过四年．此法简单易行，又有较强的可重复性，因此，Ｍ／Ｖ指数不失为有应用价值的判断胃癌病人预后的重要指标。

A retrospective study was peformed on 55 gastric cancer patients. The mitotic activity was measured by volume-corrected mitotic index(M/V index) on the recommendation of H. Haapasalo in all tumours.The relationship M/V index,clinical stage or histologic type and 5-year cumulative survival was studied, respectively .The results showed that M/V index and clinical stage were significantly related to overall survival,but histologic type not toit with statistical significance. The M/V index was all the best in predicting 1-year, 2-year and 4-year survival. This method is simple and economis,the reproducibility of M/V index was good in the study. It is concluded that the M/V index can used as a significant prognostic factor in gastric cancer.