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大剂量辛伐他汀治疗心绞痛合并高胆固醇血症的临床观察

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摘要 目的:观察大剂量辛伐他汀治疗心绞痛合并高胆固醇血症的临床效果。方法:选择冠心病心绞痛合并高胆固醇且心电运动试验阳性患者共84例,随机分为治疗组和对照组,对照组给予一般改善生活方式治疗,治疗组在此基础上给予大剂量辛伐他汀(40 m g/ d) 6个月,治疗前后进行心电图运动试验及血脂测定,对两组差异进行比较。结果:6个月后治疗组血TC、L DL- C显著降低(P <0 .0 5 ) ,心电运动试验阳性率明显下降(P <0 .0 5 ) ,而对照组改变不明显无统计学意义。结论:大剂量辛伐他汀治疗有良好的降脂作用,能显著减轻心绞痛合并高胆固醇血症患者运动诱发心肌缺血。
出处 《黑龙江医药科学》 2005年第2期58-59,共2页 Heilongjiang Medicine and Pharmacy
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