原发性不孕症患者舌苔脱落细胞与女性性激素的相关性研究

STUDY ON CORRELATION BETWEEN TONGUE EXFOLIATED CYTOLOGY AND FEMALE SEXUAL HORMONES OF PATIENTS WITH PRIMARY STERILITY

目的:探讨不孕症中医舌诊及舌苔脱落细胞与性激素的相关性。方法:选择6 0例原发性不孕症患者为观察对象,2 0例健康同龄妇女为对照,采用舌象、性激素、舌苔脱落细胞为指标进行研究。结果:1 观察组异常舌象百分比均显著高于对照组(P <0 . 0 1)。2 月经周期第10d对照组和观察组舌印片MI均表现为轻度右移,组间无显著差异;月经周期第2 0d观察组舌苔脱落细胞变化不明显,而对照组舌印片MI趋向中带,MV减小,两组比较差异非常显著(P <0 . 0 1)。3 月经周期第10d观察组E2 、P、PRL、P/E2 较高,与对照组比有非常显著差异(P <0 .0 1) ;月经周期第2 0d观察组P、P/E2 较对照组低,两组比有非常显著差异(P <0. 0 1) ;PRL较对照组为高,差异显著(P <0 0 5 ) ;FSH、LH、T变化不明显(P >0. 0 5 )。4 舌苔脱落细胞MI、MV与P、LH、LH/FSH非常显著相关(P <0 . 0 1) ,与E2 显著相关(P <0. 0 5 )。结论:不孕症患者舌象及舌苔脱落细胞检查反映机体性激素变化,可做为中医诊断的依据。

Objective:To approach the correlation between tongue exfoliated cytology and female sexual hormones of patients with primary sterility.Methods:60 cases with primary sterility were selected as obseved group (G_1),20 healthy women as control (G_2).Indexes of tongue picture,sexual hormones and exfoliated cytology were observed and determined. Results:①The abnormal percentage of tongue picture in G_1 was obviously higher than that in G_2.②The 10 th day of menstrual cycle,the maturation index (MI) of tongue exfoliated cytology in both two groups slightly turned right.The 20 th day of menstrual cycle,the exfoliated cytology changed unobviously in G1,MI tended toward middle zone and maturation value (MV) reduced In G_2.③The 10 th day of menstrual cycle in G_1,E_2,P,PRL and P/E_2 were higher than those in G_2,the difference was remarkably obvious.The 20 th day of menstrual cycle in G_1,P,P/E_2 was obviously lower,PRL was higher than those in G_2.FSH,LH and T changed unobviously.④MI and MV of tongue exfoliated cytology were remarkably correlated to P,LH and LH/FSH,and correlated to E_2.Conclusion:In primary sterility patients,the tongue picture and exfoliated cytology can reflect the changes of sexual hormones.