摘要
本文对未经补碘防治的IDD病区7～14岁儿童用碘油丸三种剂量分两次投药方法,以尿碘(UI)、FT3、FT4、TSH及甲状腺肿大率、患病率、发病率、有效率、治愈率为指标,经给药后半年、1年、2年、3年随访对比研究,发现各组有效期均能维持3年。但达标控制有效期大、中、小剂量组分别为3年、2年、1年。此应视为各组的防治周期。剂量和周期的选择认为边远防治条件差的重病区宜大剂量2～3年为周期;一般地区可选中剂量2年为周期;而轻病区,条件好的病区可选小剂量1年为周期的方法应属可取。大剂量者第2次投药时间取1年,可避免高碘损伤之顾虑和碘的排出过多过快之浪费。且可望维持效果更长的时间。
This treatise has made a study of three different doses of iodized oil pill administered twice for the children aged 7-14 in IDD areas without iodine supplement treatment. With UI, FT3, FT4, FSH and goiter rate, sickness rate, attack rate, effective rate and cure rate as indexes, a follow-up contrast study was made after administration for six months, one year, two years and three years respectively. It was found that efficacy time of each control group could last 3 years, but of up-to-standard control of large, moderate and small doses were respectively 3 years, 2 years and one year , which should be regarded as the period of prevention and treatment. It followed that selection of period and dosage should be 2 or 3 years and large doses for those in severe IDD areas; 2-year period and moderate doses for those in moderate IDD areas; and one year period and small doses for those in mildIDD areas with good medical condition. The second dose for those in severe IDD areas should be ad-ministered one year after the first, which could avoid harm caused by too much iodine and waste because of too much iodine discharged. Moreover, time of efficacy would last longer.
出处
《中国地方病防治》
北大核心
1994年第4期193-196,共4页
Chinese Journal of Control of Endemic Diseases
