摘要
通过应用ConA诱导的^3H-TdR标记的淋巴细胞转化试验,对比观察了羊、牛、猪三种布鲁氏菌的国际参考菌株16M、544A、1330S三种不同品系小鼠CBA、C57,BL,Balb/c淋巴细胞转化的不同影响。
An experimental study was carried out on the effect of Br. melitensis16, Br. abortus 544 and Br. suis 1330 on lymphocyte blastogenesiS transformation (LBT) in C57BL, Balb/c and CBA inbred mice by using 3H-TdR labelled technique. It was shown that the LBT in C57BL mice infected with Br. melitensis 16 was suppressed significantly H and 20 days post infection (P> 0. 05). But the LBT returned to normal level after 30 days gradually. A significant suppression was also observed in CBA mice infected with Br. abortus 544 and Br. suis 1330 strains 180 days post infection (P <0. 05). Nevertheless, there was no significant effect on LBT in CBA mice which infected with Br. melitensis ] 6. There was no obvious difference among the three strains of Brucella in Balb/c mice as compared with the control group (P> 0. 05).
出处
《中国地方病防治》
CAS
北大核心
1994年第5期268-270,共3页
Chinese Journal of Control of Endemic Diseases