摘要
通过饮水中加硒（０．５０μｇ／Ｌ）、加氟（５０ｍｇ／Ｌ）的方法，研究了硒氟联合作用对大鼠体内活性氧自由基（Ｒ·）和脂质过氧化物（ＬＰＯ）的影响。结果表明加氟可使机体Ｒ·和ＬＰＯ水平升高，加硒可拮抗氟的这种作用。提示可以通过加硒来拮抗地方性氟中毒所致的非骨相损伤。
This paper employed a method of adding selenium(0.5mg/L),fluoride(50mg/L)to water,observing the combined effects on active oxygen radicals(R) and lipid peroxides(LPO)of rats.The result showed that flouride can increase the level of R and LPO,selenium can antagonize the effect of fluoride,This suggested that nonskeletal damages of endemic finorosis could be antagonized by giving appropriate amount of selenium.
出处
《中国地方病学杂志》
CAS
CSCD
1994年第4期213-214,共2页
Chinese Jouranl of Endemiology
关键词
硒
氟
氧
自由基
过氧化脂质
Selenium
Fluoride
Active oxygen radicals
Lipid peroxides
