茴香醛的合成工艺

Study of the Synthesis of Anisaldehyde

以液相催化反应后的反应液(主成份为对羟基苯甲醛)为原料,碱性条件下和硫酸二甲酯于回流温度均相反应制取茴香醛,并分析了溶剂,体系酸度对反应及副反应的影响.研究发现,甲醇溶剂对对羟基苯甲醛的歧化等副反应有明显的抑制效果.另外,适当控制反应体系的酸碱性也有利于反应选择性的提高.

Methylate p-hydroxylbenzaldehyde derived from the liquid catalysis reaction, with (CH3)2SO4 directly under basic condition to produce anisaldehyde. And the influences of the acidity of the system and solvent used on the reaction and side reactions are also discussed. It's found that the solvent methanol can significantly inhibit the side reactions of p-hydroxybenzaldehyde, and that the appropriate pH of the system can be beneficial to the selectivity of the reaction.