低分子右旋糖酐联合复方丹参辅佐治疗过敏性紫癜临床观察

目的探讨低分子右旋糖酐联合复方丹参辅佐治疗过敏性紫癜临床疗效及对体内高凝状态的影响。方法对52例过敏性紫癜患儿随机分成两组,对照组给予钙剂、维生素C、扑尔敏、肾上腺皮质激素治疗,观察组在对照组治疗的基础上加用低分子右旋糖酐联合复方丹参辅佐治疗,治疗前、治疗后测定血浆D-二聚水平。结果治疗组总有效率为92.9%;对照组总有效率75.0%,经统计学处理,有显著性差异(P<0.05)。观察组治疗后血D-二聚体值低于对照组,两组差异有显著性意义(P<0.05)。结论低分子右旋糖酐联用丹参辅佐治疗疗效显著,能显著降低D-二聚体的水平,有效地逆转HSP患儿的血液高凝状态。

Objective To study the treatment efficacy with the dextrani combining with compositive salvia mitiorrhizel to anaphylatoid purpura and the effect on tendency toward thrombosis. Method 52 patients with anaphylatoid purpura were grouped into two groups randomly , control group (treatment with calcium ,Vitamin C ,chlorpheniramine ,corticosteroid ) and treatment group(treatment with dextrani combining with compositive salvia mitiorrhizel besides the same medication as control group ), the level of serum D-dimer was tested before and after treatment .Result Efficacy rate in total is 92.9% in treatment group while 75.0% in control group (P<0.05).The level of serum D-dimer in treatment group after treatment is lower than control group (P<0.05).Conclusion The treatment efficacy of dextrani with compositive salvia mitiorrhizel is much more obvious ,the level of D-dimer can be decreased apparently , The tendency toward thrombosis of HSP children is reversed effectively.