期刊文献+

紫外辐射致皮肤郎格罕氏细胞损伤的量效关系的实验研究 被引量:2

A Laboratory Study of Dose-Effect Relationship of Ultraviolet Irradiation on Langerhans Cell
下载PDF
导出
摘要 用郎格罕氏细胞(LC)、迟发型变态反应(DTH)为指标,以太阳荧光灯为光源,进行亚慢性动物实验。结果表明,1/8红斑剂量(MED)为较安全剂量,持续照射不能引起LC数目及形态变化,仍能诱导正常的DTH反应;而1MED持续照射则能引起免疫抑制,表现为LC数目减少.形态异常,不能诱导正常的DTH反应。提示我们在医疗卫生及实际生活中,应避免此剂量的持续照射,以免发生免疫抑制。 The purpose of this exxperiment was to discuse the longterm effect at low level on immune system. A subchronic experiment was carried out to using Langerhans cell and DTH asindicators and fluorescent sunlamps as source.The resultsshow that 1 /8 MED of UVR is safety on immunology and cannot show obvious immune suppression whereas I MED ofUVR show obvious immune suppression.It show that thenumber of LC decreased and the response of DTH suppressed.It should be avoid to long term exposure to such a dose levelof UVR in daily life and in health service. The results providethe basis for establishing limitation for long term UV exposure
出处 《中国公共卫生学报》 1994年第2期104-106,共3页
关键词 放射损伤 郎格罕氏细胞 紫外线 Ultraviolet radiation Langerhans CellDTH
  • 相关文献

同被引文献22

  • 1唐军民,MDACC,ML Kripke,K Dunner Jr,C Bucana.正常及紫外线照射小鼠抗原呈递细胞在接触性过敏反应中的特性[J].北京医科大学学报,1993,25(5):363-365. 被引量:2
  • 2WE保罗.基础免疫学[M].北京:科学技术出版社,2003.460-501.
  • 3张学军 刘维达 何春涤.现代皮肤病学基础[M].北京:人民卫生出版社,2001.1068.
  • 4Kohl K,Klein E,Koch S,et al.Migration and differentiation of Langerhans cell precursors[J].Eur J Cell Biol,2004,83(11-12):805-811.
  • 5Sting G,Kata S,Green I.The functional role of Langerhans cells[J].J Invest Dermatol,1980,74:548.
  • 6Stingl G,Wolff-Schreiner ECh,Pichler W J,et al.Epidermal Langerhans cells bear IgG-Fc and C3 receptors[J].Nature,1977,268:245.
  • 7陈洪铎 袁景涛 王雅坤 等.用ATP酶染色检查人及豚鼠Langerhans细胞的研究.中国医科大学学报,1984,13(1):1-1.
  • 8Juhlin L,Shelley W B.New staining techniques for the Langerhans cell[J].Acta Dermatovener,1977,57(3):289.
  • 9Robins P G,Brandon D.A modification of the adenosine triphosphatase method to demonstrate epidermal Langerhans cells[J].Stain Technology,1981,56:87.
  • 10谷华运 苏兆绛 陈移.用ATP酶法显示表皮内的郎格罕氏细胞.解剖学杂志,1985,8:165-167.

引证文献2

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部