脑白质疏松症与颈动脉粥样硬化斑块关系的对比研究

The ralationship between leukoaraiosis and carotid atheromatous plaque

目的探讨脑白质疏松症(leukoaraiosis,LA)与颈动脉粥样硬化斑块的关系,以期达到干预、减缓LA的发生和发展。方法对136例LA患者和124例非LA患者行颈动脉双功能彩色多普勒超声检查,进行临床对比分析。结果LA组颈动脉粥样硬化斑块的检出率为86.29%,软斑、溃疡斑占80.34%,颈动脉中、重度狭窄率分别为52.99%、22.22%,与非LA组相比,均有极高度显著性差异(P<0.01)。LA组的LA严重程度分别为I级26.47%、Ⅱ级52.94%、Ⅲ级20.59%,与颈动脉狭窄程度呈正相关。结论颈动脉粥样硬化斑块、颈动脉狭窄程度及其软斑、溃疡斑分别与LA有较强相关性,能预示LA的发生、发展及其严重程度。

Objective To investigate the relationship betwee n the leukoaraiosis(LA) and carotid atheromatous plaque and to achieve the goal of preventing happening and reducing development of LA. Methods The carotid artery of 136 LA patients and 124 non -LA patients were examined using dopple ultrasonography. The means of both grou ps were contrasted analysis. Results In the LA group, the detectable rate of carotid a theromatous plaques was 86.29%, the rate of soft plaques and ulcerous plaques wa s 80.34%, the rates of medium stenosis and serious stenosis were 52.99% and 22.2 2%. These rates were all higher than the non-LA group (P<0.01). The serious levels of LA were shown that I grade was 26.47%, II grade was 52.94%, III grade 20.59. Conclusion Carotid atheromatous plaque and carotid stenos al level and the soft plaques,ulcerous plaques are closely ratation with LA.