海绵AXINYSSA SP的化学成分研究

STUDIES ON THE CONSTITUENTS OF MARINE SPONGE AXINYSSA SP.

从海绵Axinyssa sp中分离到6种化合物,经光谱解析鉴定了2个成分的结构。一个为新的过氧基甾醇,命名为Axinysasterol(1),结构为5α,8α—环二氧基—6,22,25—三烯—3β—麦角甾醇;另一化合物为(6R,7S)—7—氨基—7,8—二氢—α—比萨烯氯化物(2)。

A new 5a, 8a - epidioxy sterol named Axinysasterol (1) with a known compound (6R, 7S)-7-amino-7, 8-dihydro-a-bisaboIene hydrochloride (2) was isolated from the Okinawa marine sponge Axinyssa sp. The structure of Axinysasterol (1) deduced as 5a, 8a-epidioxyergosta - 6,22,25-trien-3B-ol on the basis of chemical and spectral evidence.