摘要
通过生物信息学和系统发育学分析,研究了苦味受体和甜味 /鲜味受体的进化途径。结果显示,苦味受体和甜味 /鲜味受体在进化上具有远相关,并且具有不同的进化途径,提示这可能是导致这些受体具有不同功能,传导不同味觉的原因。
In this study,we investigated the evolutionary pathways of bitter,sweet and umami receptors using bioinformatic and phylogenetic analyses.Our results showed that the distantly evolutionary relationship between bitter and sweet/umami receptors.Our results also showed that bitter and sweet/umami receptors have differently evolutionary pathways,suggesting that the different evolutionary pathways may resulte in the differences of these three receptors in function.
基金
国家自然科学基金
中科院创新基金 (编号:KSCX2 1 05 )
中科院研究生创新项目资助
关键词
进化途径
苦味受体
甜味受体/鲜味受体
基因融合
跨膜区
evolutionary pathways
bitter taste receptor
sweet/umami taste receptor
gene fusion
transmembrane domain