摘要
采用乳液聚合法对微泡超声造影剂的制备进行研究,重点对反应中所必需的乳化剂进行选择,并在此基础上讨论了乳化剂的用量及配比等对实验结果的影响.由本方法所制得的微泡粒径以2～8 μm的居多,浓度在9.51×109 /ml左右,单体转化率达到71%,有利于更进一步的研究.
The preparation of ultrasound contrast agent (UCA) by emulsion polymerization was studied. The study focus on the selection of the emulsifier which is necessary in the preparation. Then the effect of the emulsifier dose and ratio on the experimental results was studied. The microbubbles were prepared by this method had a diameter of 2 to 8 μm, concentration of 9.51×10 10 /ml,and the monomer conversion rate was up to 71%, worthy of much more research.
出处
《中国医学影像技术》
CSCD
北大核心
2005年第4期501-503,共3页
Chinese Journal of Medical Imaging Technology
基金
国家自然科学基金资助(30370579)。
关键词
乳液聚合
乳化剂
单体转化率
超声造影剂
微泡
Emulsion polymerization
Emulsifier
Monomer conversion
Ultrasound contrast agents, microbubbles
