3cm以下肺腺癌与鳞癌的CT同层动态增强研究

Single-location dynamic enhanced CT for lung adenocarcinoma and squamous carcinoma with diameter <3 cm

目的 评价同层动态增强CT技术对3 cm以下肺腺癌和鳞癌的诊断价值。方法 选择直径<3 cm的肺腺癌22例和肺鳞癌9例,平扫后静脉注入对比剂行同层动态增强CT扫描,测量其增强前后各时间段的CT值改变,计算最大CT强化值,绘制其时间密度曲线。结果 肺腺癌在增强后135 s和195 s时间段的CT强化值大于鳞癌,二者有明显统计学差异(P<0.05),余各时间段无明显差别(P>0.05)。腺癌的时间密度曲线为缓慢持续上升型,鳞癌为抛物线型。肺腺癌与鳞癌的增强效果皆始于35 s,但鳞癌峰值时间早于腺癌,二者峰值大小无统计学差异(P>0.05)。结论 同层CT动态增强扫描技术,在区分肺腺癌与鳞癌组织学类型方面有一定价值。

Objective To evaluate the diagnostic value of single-location dynamic enhanced CT for lung adenocarcinoma and squamous carcinoma with diameter <3 cm. Methods Single-location dynamic enhanced CT in the patients with lung adenocarcinoma (22 cases) and lung squamous carcinoma (9 cases) were analyzed, and the time-intensity curves were created. Results The average degree of enhancement of lung adenocarcinoma were higher than that of squamous carcinoma in 135 s and 195 s ( P <0.05), and the other times were not significantly different (all P >0.05). The time-intensity curve of adenocarcinoma increased slowly, while squamous carcinoma's curve looked as a parabola and showed a slowly progress and then decreased slowly. Both enhanced start time of adenocarcinoma and squamous carcinoma began from 35 s, the peak time of squamous carcinoma was earlier than that of adenocarcinoma, the peak height of lung adenocarcinoma was higher than that of squamous carcinoma, but they were not significantly different ( P >0.05). Conclusion Single-location dynamic CT is helpful in differential diagnosis of lung adenocarcinoma and lung squamous carcinoma.