骨质疏松症对口腔颌面部骨骼的影响(英文)

Effects of osteoporosis on oral and maxillofacial bone

目的:口腔颌面部骨骼作为全身骨骼的一部份,影响全身骨质疏松的因素同样也可影响颌骨。本文拟对由口腔颌面部骨质疏松引起的牙槽骨吸收、牙周病、种植体愈合、颞颌关节疾病与全身性骨质疏松的关系研究进展作一综述。资料来源:应用计算机检索Medline数据库1990-01/2003-12的相关文章,检索词“Osteoporosis,alveolaratrophy,periodontitis,implantden-ture,temporarymandiblejoint.”限定文章语言种类为英文,同时计算机检索中国期刊全文数据库、万方数据库1990-01/2003-12的相关文章,检索词:“骨质疏松、牙槽骨萎缩、牙周病、种植牙、颞下颌关节”,限定语言种类为中文。资料选择:对资料进行初审,选取试验包括上述治疗组和对照组的文献,然后筛除非随机临床试验的研究,对剩余的文献开始查找全文,以随机对照临床试验(RCT)作为纳入标准。排除标准:重复性研究。资料提炼:共收集到27篇关于全身性骨质疏松和牙槽骨萎缩、牙周病、种植义齿、颞下颌关节疾病关系的随机和未随机试验。纳入的18个试验符合纳入标准。资料综合:18个试验的对象均为符合诊断标准的骨质疏松症患者,通过对骨密度、剩余牙数、牙槽嵴高度等检测方法,对全身性骨质疏松引起的口腔颌面部骨骼的变化进行了对照研究及相关分析。

OBJECTIVE:As a part of the whole skeleton,oral maxilloficial bone can also be affected by the risk factors of systemic osteoporosis. This paper reviewed literature on the possible correlation of systemic osteoporosis with oral alveolar bone resorption,periodontal disease,healing of implanted denture and temporomandibular joint disease that result from oral maxillofacial osteoporosis.DATA SOURCES:Literature in English between January 1999 and December 2003 were searched with the computer in Medline Database by the following key words:osteoporosis,alveolar trophy, periodontitis,implanted denture and tempororomandibular joint with; meanwhile literature was also searched in Chinese Periodical Database and Wanfang Database of the same period by the same key words in Chinese.STUDY SELECTION:Literature involving treatment group and control group were screened in the first trial.Then those non randomized clinical trials were excluded and the others were looked up for full text.Inclusion criteria:randomized controlled clinical trial(RTC).Exclusion criteria:repeated study.DATA EXTRACTION:A total of 27 articles of randomized or non randomized studies on the possible association of systemic osteoporosis with oral alveolar bone atrophy,implanted denture and temporomandibular joint disease were collected, and 18 trials met the inclusion criteria.DATA SYNTHESIS:All subjects in the 18 studies were confirmed of having osteoporosis according the diagnostic standards.Changes of oral maxillofacial bone in systemic osteoporosis were explored by observing bone density,residual teeth,the height of alveolar ridge so as to make comparative and correlation analysis.CONCLUSION:In systemic osteoporosis,mandible bone may also have rarefaction changes.