阻塞性睡眠呼吸暂停低通气综合征的性别差异及临床特点

Clinical characteristics of sleep apnea-hypopnea syndrome in women and men

目的:通过对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的流行病学调查及(PSG)监测,了解女性患者不同于男性患者的临床特点。方法:比较OSAHS男、女性患者之间多项指标及多导睡眠监测记录。参考美国睡眠医学会(1999)及中华医学会耳鼻咽喉科学分会(2002)推荐的杭州诊断标准,应用SPSS11.0进行统计学处理。结果:女性患者平均年龄为(53.4±15.8)岁,男性患者平均年龄为(41.6±20.2)岁,年龄差异有统计学意义(P<0.05)。平均体质指数与男性患者比较,差异无统计学意义。女性患者AHI为32.8±12.6,男性患者为49.9±25.8,差异有统计学意义(P<0.05),女性患者平均最低血氧饱和度为(70.0±11.1)%,男性患者为(71.0±12.2)%,差异无统计学意义。结论:女性SAHS患者年龄大于男性患者,平均AHI较男性患者低,以低通气为主。

Objective:To study the clinical characteristics of female patients with obstructive sleep apnea- hypopnea syndrome (OSAHS) by epidemiological investigation and polysomnography study,compared with that of male patients.Method:Several indexes and the result of polysomnography study of women and men with OSAHS were compared.Result:The mean age of female patients was 53.4±15.8 years old, and that of male patients was 41.6±20.2, the difference was considered significant.The difference of the mean body mass index (BMI) had no significance.The mean apnea-hypopnea index (AHI) of female patients was 32.8±12.6,and that of male patients was 49.9±25.8,P<0.05, the difference was considered significant.The mean lower oxygen saturation of female patients was(70.0±11.1)%,and that of male patients was(71.0±12.2)%,the difference had no significance.Conclusion:Female patients with SAHS are older than male patients,the mean AHI of female patients is lower than that of male patients, but the mean HI (hypopnea index) of female patients is higher than that of male patients.