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外科治疗伴浸润性突眼的原发性甲状腺机能亢进患者的临床研究 被引量:1

Subtotal thyroidectomy in the treatment of Grave's ophthalmopathy
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摘要 为探讨甲状腺次全切除术对原发性甲状腺机能亢进(甲亢)患者浸润性突眼的影响,笔者将61例患者随机分为治疗组及对照组,治疗组31例以双侧甲状腺次全切术治疗为主,辅以甲状腺素片口服,对照组30例以药物治疗为主,两组分别在治疗前及治疗6个月和1年后检查眼球突出度,并作疗效评价。结果示两组治疗后6个月,1年后突眼度无显著性差异(P>0.05),两组总有效率无显著性差异(P>0.05),两组在治疗后TT3,TT4,TSH水平差异显著(P<0.05),而治疗组高代谢症候群均消失。结论对于伴浸润性突眼的甲亢患者,还是可以进行手术治疗的。
出处 《中国普通外科杂志》 CAS CSCD 2005年第4期315-317,共3页 China Journal of General Surgery
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参考文献10

  • 1张天钧.Graves眼病的诊断及治疗[J].中华内分泌代谢杂志,2000,16(3):196-197. 被引量:11
  • 2吴阶平 裘法祖.黄家驷外科学[M].北京:人民卫生出版社,2002.1410.
  • 3陈灏珠.实用内科学[M]:第10版[M].北京:人民卫生出版社,1998.828-868.
  • 4陈灏珠.内科学[M](第四版)[M].北京:人民卫生出版社,1996.724.
  • 5朱显军,安振梅,魏松全.促甲状腺激素受体在Graves眼病发病中的作用研究进展[J].国外医学(内分泌学分册),2000,20(4):179-182. 被引量:5
  • 6Bohn RS. Understanding the immunology of Graves ' ophthalmopathy. Is it an autoimmune disease ? [ J ]. Endocrinol Metab Clin North Am,2000,80(2) :287 -296.
  • 7Wiersinga WM , Prummel MF. An evidence based approach to the treatment of Graves 'ophthalmopathy [ J ] . Endocrinol Metab Clin North Am, 2000,29(2) :297 -319.
  • 8Bartalena L, Marcoccic C, Bogazzi F, et al. Relation between theraoy for hyperthyroidism and course of Graves 'ophthalmopathy [J]. N Engl Jmed,1998,338(2) :73 -78.
  • 9Marcocci C,Bruno Bossio G,Mannetti L, et al. The course of Graves'ophthalmopathy is not influenced by near totalthyroidectomy: a case control study [ J]. Clin Endocrinol, 1999, 51(4) :503.
  • 10Dietlein M , Dederichs B , Weigand A , et al. Radioiodinetherapy and thyroid associated orbitopathy: risk factors and preventive effects of glucocorticoids [ J ]. Exp Clin Endocrinol Diabetes,1999,107(Suppl5) :190 - 194.

二级参考文献29

  • 1HeufelderAE.PathogenesisofGraves′ophthalmopathy:recentcontroversiesandprogress[J].EurJEndocrinol,1995,132:532~541.
  • 2McgregorAM.HasthetargetautoantigenforGraves′ophthalmopathybeenfound[J]?Lancet,1998,352:595~596.
  • 3StadlmayrW,BichlrmairAM,SpitzwegC,etal.DetectionofribonucleicacidencodingfulllengthhumanthyrotropinreceptorinorbitalandpretibialfibroblestofpatientswithGraves′ophthalrmopathyandpretibialmyxedema[J].Thyroid,1997,7:3~12.
  • 4BurmanKD.Graves′ophthalmopathy:Whatistheinitialabnormality[J]?EurJEndocrinol,1997,136:583~585.
  • 5HenfelderAE.InvolvementoftheorbitalfibroblastandTSHreceptorinthepathogenesisofGraves′ophthalmopathy[J].Thyroid,1995,5:331~340.
  • 6PaschkeR,LudgateM.Thethyrotropinreceptorinthyroiddisease[J].NEnglJMed,1997,337:1675~1681.
  • 7SandeJV,ParmaJ,TonaccheraM,etal.SomaticandgermlinemutationoftheTSHreceptorgeneinthyroiddisease[J].JClinEndocrinolMetab,1995,80:2577~2585.
  • 8BryanM,JohnCM.ThepathogenesisofGraves′disease[J].EndocrinolMetabClinNorthAm,1998,27:73~89.
  • 9BahnRS,DuttonCM,HeufelderAE,etal.AgenomicpointmutationintheextracellulardomainofthethyotropinreceptorinpatientswithGraves′ophthalmopathy[J].JClinEndocrinolMetab,1994,78:256~260.
  • 10SpitzwegC,JobaW,HuntN,etal.Analysisofhunanthyrotropinreceptorgeneexpressionandimmunoreactivityinhumanorbitaltisue[J].EurJEndocrinol,1997,136:599~607.

共引文献107

同被引文献5

  • 1陈灝珠.内科学[M].4版.北京:人民卫生出版社,1996:672.
  • 2Bhansali SK,Chandalia HB.Thyotoxicosis-surical management inthe era of evidence-based medicine:experience in western Indiawith 752 cases [J].Asian J Surg,2002,25(4):291-299.
  • 3Stalberg P,Svensson A,Hessman O,et al.Surgical treatment ofGraves'disease:evidence-based approach [J].World J Surg,2008,32(7):1269-1277.
  • 4刘超,郭剑津.Graves眼病治疗模式的合理选择[J].中国实用内科杂志,2010,30(3):286-288. 被引量:3
  • 5曹明明,童南伟.Graves眼病的诊断和治疗[J].内科理论与实践,2010,5(2):177-179. 被引量:6

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