免疫接种后牛血清与乳汁中特异性抗体效价的比较

The differences of the Antibody titer in Serum and Milk after Immunization in Cow

目的:研究孕牛经免疫接种后,血清及乳汁中特异性抗体效价的变化关系。方法:以9株人肠道病原菌制备的混合抗原对孕牛进行系统免疫,分娩后收集血液和乳汁,检测其中特异性抗体的效价。结果:血清中抗体效价120d内始终维持在210～212,而常乳中抗体的效价120d内也能维持在26～27。结论:经过反复加强免疫使血清中特异性抗体效价始终维持在较高水平,就能保证乳计中特异性抗体效价维持在一定水平。

Objective: To study the relation of the antibody titer in serum and milk after immunization. Methods: Selecting 3 strains pathogenic E.coli, 3 strains Salmonella and 3 strains Shigella as antigens to make the mixed vaccine, and gestation cows were immunized systemically. After parturition the blood and the milk were collected and researched the change of the specific IgG. Results: It was found that the antibody titers in blood were 2^(10)~2^(12), the antibody titers in immune milk were 2\+6~2\+7. Conclusion: The antibody titers in immune milk can maintain some level so long as the antibody titers in blood can maintain a high level.