经五氯酚钠浸泡后钉螺脑神经节的超微结构变化

ULTRASTRUCTURAL CHANGE OF BRAIN GANGLION OF ONCOMELANIA HUPENSIS AFTER IMMERSION IN SODIUM PENTACHLOROPHENATE

本文在透射电镜下首次观察了湖北钉螺脑神经节的纤维鞘、神经节胞体区和神经纤维网的超微结构，经五氯酚钠浸泡后，钉螺脑神经节的超微结构发生改变，神经细胞和神经纤维内的线粒体由变性至坏死，神经细胞内的糖原含量显著减少，神经纤维网也发生变性坏死，为阐明五氯酚钠对钉螺中枢神经系统的作用机制提供了超微结构的依据。

The ultrastructure of the fibrous sheath,the layer of ganglionic cell bodies and the neuropil of brain ganglion of Oncomelania hupensis was first observed under transmission electron microscope. Ultrastructural changes were found in the brain ganglion after immersing the snails in sodium pentachlorophenate.The mitochondria of nerve fibers and neurons showed denaturation and necrosis,and glycogen in neurones was markedly reduced;the neuropil also exhibited denaturation and necrosis.The ultrastructural findings may explicate in some way the mechanism of molluscicidal action of NaPcP on Oncomelania hupensis via its action on the nervous system(Figs.1-6).