衣原体的Ⅲ型分泌系统
摘要
研究发现衣原体和很多革兰阴性菌病原体一样具有Ⅲ型分泌系统,它们通过Ⅲ型分泌系统将各种毒力蛋白注入宿主细胞(真核细胞)内影响宿主细胞正常新陈代谢及功能,并建立适于寄生的亚细胞小环境。这种Ⅲ型分泌系统可能对揭示衣原体的致病机制有重要意义。文中主要介绍了衣原体的Ⅲ型分泌系统及其在衣原体中的作用。
出处
《国外医学(皮肤性病学分册)》
2005年第3期157-159,共3页
Foreign Medical Sciences(Section of Dermatology and Venereology)
参考文献22
-
1Nguyen L, Paulsen IT, Tchieu J,et al. Phylogenetic analyses of the constituents of Type Ⅲ protein secretion systems. Mol Microbiol Biotechnol,2000 ,2 : 125 - 144.
-
2Dale C, Young SA, Haydon DT, et al. The insect endosymbiont Sodalis glossinidius utilizes a type 111 secretion system for cell invasion.Proc Natl Acad Sci U S A, 2001, 98:1883 -1888.
-
3Kubori T, Matsushima Y, Nakamura D, et al. Supramolecular structure of the Salmonella typhimurium type Ⅲ protein secretion system.Science, 1998, 280:602 - 605.
-
4Hueck CJ. Type Ⅲ protein secretion systems in bacterial pathogens of animals and plants. Microbiol Mol Biol Rev, 1998, 62:379-433.
-
5Kim JF. Revisiting the chlamydial type Ⅲ protein secretion system:clues to the origin of type Ⅲ protein secretion. Trends Genet, 2001,17:65 - 69.
-
6Mills SD, Boland A, Sory MP,et al. Yersinia enterocolitica induces apoptosis in macrophages by a process requiring functional type Ⅲ secretion and translocation mechanisms and involving YopP, presumably acting as an effector protein. Proc Natl Acad Sci U S A, 1997, 94:12638 - 12643.
-
7Zhou D, Mooseker MS, Galan JE. Role of the S. typhimurium actinbinding protein SipA in bacterial internalization. Science, 1999,283:2092 - 2095.
-
8Galan JE, Collmer A. Type Ⅲ secretion machines: bacterial devices for protein delivery into host cells. Science, 1999, 284 : 1322 - 1328.
-
9Bavoil PM, Hsia RC. Type Ⅲ secretion in Chlamydia: a case of deja vu? Mol Microbiol, 1998, 28:860 - 862.
-
10Hsia RC, Pannekoek Y, Ingerowski E, et al. Type Ⅲ secretion genes identify a putative virulence locus of Chlamydia. Mol .Microbiol,1997, 25:351 -359.
-
1武晓莉,商庆新,殷德民,李卿,蔡泽浩,刘伟.FGFR1在增生性瘢痕和正常皮肤中的表达[J].实用美容整形外科杂志,2003,14(6):329-331.
-
2陈光,郝树萍.急性脊髓损伤后局部亚细胞与膜结构改变及654—2治疗的实验观察[J].中国骨伤,1992,5(4):8-9.
-
3程飚,付小兵,盛志勇.脂肪与创面愈合[J].感染.炎症.修复,2003,4(2):122-124. 被引量:3
-
4王志利,侯林生.脑弥漫性轴索损伤的研究现状及新进展[J].海南医学,2007,18(7):149-152. 被引量:7
-
5徐锐.弥漫性轴索损伤的临床研究进展[J].中国医药指南,2013,11(17):76-77. 被引量:3
-
6卫小春,张志强,韩来春.甘露醇对肢体缺血再灌注损伤的保护作用[J].中华骨科杂志,1995,15(6):370-372. 被引量:53
-
7刘卫珍,杨金凤.奥曲肽对兔肝缺血再灌注后肺损伤的影响[J].中国医师杂志,2010,12(5):629-632.
-
8刘军,陈廖斌,汪晖,商亮,刘岩松,张觅,Magdalou Jacques.当归多糖对大鼠骨性关节炎形态改变的影响[J].武汉大学学报(医学版),2010,31(5):608-612. 被引量:16
-
9杨宇强,李瑞峰.体外循环期胰岛素抵抗的研究新进展[J].中国体外循环杂志,2004,2(2):122-124. 被引量:12
-
10迟路湘,杨宗城,吴军,张宁,陈希炜,黎鳌.严重烧伤早期心肌细胞膜阴离子位点、亚细胞钙的变化[J].中华物理医学杂志,1998,20(4):248-249. 被引量:1