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端粒酶与喉癌相关性研究进展 被引量：2

Telomerase and laryngeal squamous cell carcinoma
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摘要 端粒酶激活与恶性肿瘤发生发展之间存在着密切的关系。本文就端粒酶结构、功能及其与喉癌发生发展关系的最新研究进展作简要综述。 Telomerase, a ribonucleoprotein enzyme, is a key component in maintaining the development of malignant tumor. This article introduced the latest research results on the structure and function of telomerase and summarized the relationship between telomerase and laryngeal squamous cell carcinoma.
作者 陈志凌 吴正虎
机构地区 中国医科大学附属一院耳鼻咽喉科 杭州市第二人民医院耳鼻咽喉科
出处 《中国耳鼻咽喉颅底外科杂志》 CAS 2005年第2期125-128,共4页 Chinese Journal of Otorhinolaryngology-skull Base Surgery
基金 杭州市医药卫生科技项目(2004A011)。
关键词 端粒酶 喉癌 Telomerase Larngeal squamous cell larcinoma
分类号 R730.231 [医药卫生—肿瘤] Q55 [生物学—生物化学]
  • 相关文献

参考文献17

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二级参考文献31

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共引文献12

同被引文献25

  • 1骆志国,周福祥,周云峰,谢丛华,代静,潘东风,刘诗权.鳞癌细胞株放射敏感性与端粒酶活性及端粒长度变化的关系[J].中华放射医学与防护杂志,2005,25(3):232-235. 被引量：10
  • 2费声重,吴正虎.喉癌与人乳头状瘤病毒相关性研究的进展[J].中华耳鼻咽喉科杂志,1995,30(2):115-118. 被引量：24
  • 3肖红俊,孔维佳,汪广平,杨成章,龚树生,王彦君,李明.喉癌切除术后患者的生存质量[J].中国康复,2006,21(1):37-38. 被引量：26
  • 4熊杰,廖正凯,周福祥,谢丛华,鲍洁,刘诗权,周云峰.辣根过氧化物酶/吲哚乙酸系统作为基因导向性酶前体药物疗法的研究[J].武汉大学学报（医学版）,2006,27(5):560-563. 被引量：3
  • 5Horikawa I, Cable PL, Mazur SJ, et al. Downstream E-box-mediated regulation of the human telomerase reverse transcfiptase (hTERT) gene transcription: evidence for an endogenous mechanism of transcriptional repression. Mol Biol Cell, 2002, 13(8) :2585-2597.
  • 6Greco O, Folkes LK, Wardman P, et al. Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-aeetie acid. Cancer Gene Ther, 2000, 7 ( 11 ) :1414-1420.
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  • 8Cong YS, Wright WE, Shay JW. Human telomerase and its regulation. Microbiol Mol Biol Rev, 2002, 66(3):407-425.
  • 9Luzar B, Poljak M, Matin IJ, et al. Telomerase reactivation is an early event in laryngeal carcinogenesis. Mod Pathol, 2003, 16 (9) :841-848.
  • 10Luzar B, Poljak M, Marin IJ, et al. Quantitative measurement of telomerase catalytic subunit (hTERT) mRNA in laryngeal squamous cell carcinomas. Anticancer Res, 2001, 21(6A):4011-4015.

引证文献2

二级引证文献4

中国耳鼻咽喉颅底外科杂志
2005年 第2期

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