恶性肿瘤化疗耐药评价体系的研究进展
被引量：1
Progress in the evaluation systems for multidrug resistance in malignant tumors chemotheray
摘要
化疗是恶性肿瘤的重要治疗手段,然而由于患者个体差异所导致的药物作用不敏感或者耐药性产生是影响疗效的最重要因素。目前已有许多肿瘤耐药评价方法和耐药指标应用于科研和临床,现就近年来化疗耐药评价领域的研究进展作一简要回顾,并重点分析了耐药评价指标与应用前景。
出处
《国外医学（肿瘤学分册）》
2005年第5期355-358,共4页
Foreign Medical Sciences (Cancer Section)
参考文献17
-
1Furukawa S. In vitro chemosensitivity of hepatocellular carcinoma for hepatic arterial infusion chemotherapy using the MTT assay with the combinations of antitumor drugs. Kurume Med J, 2004,51 ( 1 ): 25-33.
-
2Ng TY,Ngan H, Cheng D,et al. Clinical applicability of the ATP cell viability assay as a predictor of chemoresponse in platinum-resistant epithelial ovarian cancer using nonsurgical tumor cell samples. Gynecol Onco1,2000,76 ( 3 ) :405-408.
-
3Sharma S, Neale MH, Di Nicolantonio F,et al. Outcome of ATP based tumor chemosensitivity assay directed chemotherapy in heavily pretreated recurrent ovarian carcinoma. BMC Cancer,2003,3 ( 1 ): 19.
-
4Mollgard L,Tidefelt U,Sundman Engberg B,et al. In vitro chemosensitivity testing in acutenonlymphocytic leukemia using the bioluminescence ATP assay. Leuk Res,2000,24(5) :445-452.
-
5Dean M, Rzhetsky A, Allikmets R. The human ATP- binding cassette(ABC) transporter superfamily. Genome Res , 2001,11 (7): 1156-1166.
-
6Stavrovskaya AA. Cellular mechanisms of multidrug resistance of tumor cells. Biochemistry ( Mosc ) , 2000,65 ( 1 ): 95 - 106.
-
7Grandjean F, Bremaud L,Verdier M, et al. Sequential gene expression of P- glycoprotein ( P- gp ), multidrug resistance- associated protein(MRP) and lung resistance protein: functional activity of P-gp and MRP present in the doxorubicin-resistant human K562 cell lines. Anticancer Drugs,2001,12(3) :247-258.
-
8Hatanaka H,Abe Y,Naruke M,et al. Modulation of multidrug resistance in a cancer cell line by anti-multidrug resistance-associated protein (MRP) ribozyme. Anticancer Res, 2001,21 ( 2 A ): 879- 885.
-
9Homem de Bittencourt PI Jr, Curi R. Antiproliferative prostaglandins and the MRP/GS-X pump role in cancer immunosuppression and insight into new strategies in cancer gene therapy. Biochem Pharmacol,2001,62(7) :811-819.
-
10Allikmets R,Schriml LM, Hutchinson A, et al. A human placentaspecific ATP-binding cassette gene (ABCP)on chromosome 4q22that is involved in multidrug resistance. Cancer Res, 1998,58 (23):5337-5339.
同被引文献3
-
1Miwa M,Ura M,Nishida M,et al.Design of a novel oral fluoropy rmidene carbamate,carecitabine,which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue[J].Eur J cancer,1998,34(8):1274-1281.
-
2王洁,刘叙仪.抗肿瘤新靶点药物及其临床应用前景[J].国外医学（肿瘤学分册）,2001,28(5):326-329. 被引量：10
-
3章宏,厉有名.二氢嘧啶脱氢酶在氟尿嘧啶化疗中的意义[J].国外医学（肿瘤学分册）,2004,31(2):120-121. 被引量：1
-
1郭晓.大剂量甲氨蝶呤治疗儿童白血病临床分析[J].世界最新医学信息文摘,2016,16(94):141-142. 被引量：1
-
2陈汝福,邹声泉,韩明.肝门部胆管癌mdr-1 mRNA的表达及与临床病理指标间的关系[J].中国现代普通外科进展,1999,2(1):28-30.
-
3樊峰,吴伟国,何影娟.乳腺癌中MDR1和GST-π的表达及临床意义[J].蛇志,2005,17(4):241-243.
-
4谭纪伏,孙茂民,赵齐,夏春林.乳腺癌中GST-π、TOPO II的表达及临床意义[J].苏州医学院学报,2001,21(6):657-658.
-
5仝娟.肌注小剂量地塞米松致低钾血症13例临床分析[J].医学理论与实践,2014,27(16):2172-2173. 被引量：2
-
6范小村,钟科.卡马西平不良反应的临床特征及相关因素分析[J].中国伤残医学,2015,23(8):142-143. 被引量：1
-
7雷招宝.他汀类药物致勃起功能障碍[J].药物不良反应杂志,2010,12(2):105-108. 被引量：4
-
8戴璋达,胡永胜.中药注射剂药品不良反应的现状及防治对策[J].海峡药学,2015,27(1):238-240. 被引量：1
-
9施湘萍.基层医院113例药品不良反应报告分析[J].中国药业,2014,23(1):52-53. 被引量：1
-
10沈祖刚,蒋惠森.欧必亭联合治疗化疗所致的胃肠道反应[J].中国肿瘤临床,2001,28(3):236-237. 被引量：11
