动脉粥样硬化性心血管病炎症的临床评价和治疗

Clinical Evaluation and Management of Inflammation in Atherosclerotic Cardiovascular Disease

血管内皮细胞功能紊乱和炎症在动脉粥样硬化及其相关疾病的进展中起重要作用,C反应蛋白、高灵敏C反应蛋白、细胞黏附因子、白细胞介素和斑块温度及斑块pH变化参与动脉粥样硬化炎症过程。现对这些炎症标志物在动脉粥样硬化炎症中的临床评价及其药物干预研究进展做一复习。

Atherosclerosis is regarded as a dynamic and progressive disease arising from the combination of endothelial dysfunction and inflammation.As the markers of inflammation,C-reactive protein,high-sensitivity C-reactive protein,cell adhesion molecules,interleukins,thermal heterogeneity and pH heterogeneity of atherosclerotic plaque are involved in the inflammation course.This review article will provide a brief overview of certain value in the clinical evaluation and management in atherosclerosis.