摘要
慢性心力衰竭心肌重塑由去甲肾上腺素、血管紧张素Ⅱ、醛固酮、炎性细胞因子、基质金属蛋白酶、内皮素、氧化应激等因素介导,其干预治疗主要有β受体阻滞剂、血管紧张素转化酶抑制剂、血管紧张素受体拮抗剂、醛固酮拮抗剂、基质金属蛋白酶抑制剂、抗细胞因子治疗及内皮素受体拮抗剂等。
Myocardial remodeling secondary to chronic heart failure can be induced by such factors as norepinephrine,angiotensin-Ⅱ,aldosterone,proinflammatory cytokines,matrix metalloproteinases,endothelin,oxidative stress,et al.The therapeutics include β blockers,angiotensin converting enzyme inhibitors,aldosterone antagonists,matrix metalloproteinase inhibitors,anticytokine therapy,endothelin receptor antagonists,et al.
出处
《心血管病学进展》
CAS
2005年第3期281-284,共4页
Advances in Cardiovascular Diseases
