生长抑素在胃镜止血治疗中的应用

Therapeutic Effect of Somatostain in Gastroscope Hemostasis

目的 观察生长抑素在上消化道出血胃镜止血治疗中的应用。方法 1996年9月～2 0 0 4年8月收治上消化道出血病人96例,患者入院后随机分为治疗组和对照组,治疗组在胃镜检查前6h予生长抑素静脉注射(2 5 0 μg/h) ,余同治疗组常规制酸止血,对症支持治疗。结果 治疗组和对照组再出血率分别为3 .8%和18% ,两组比较差异有显著性(t =5 2 4,P <0 0 5 ) ;近期手术治疗分别为1.9%和13 .6% ,差异有显著性(t =4 84,P <0 .0 5 ) ;住院时间分别为(10 .1±9.8)d和(16.3±9.2 )d(t =3 .19,P <0 . 0 1) ;住院费用分别为(12 3 62±2 3 43 )元和(12 698±2 5 64 )元(t =0 66,P >0 .0 5 )。结论 治疗组较对照组再出血率、急诊手术、住院天数明显减少,住院费用无统计学差异。

Objective To observe the therapeutic effect of somatostain in gastro scope hemostasis. [Methods] 96 cases of upper gastrointestinal hemorrhage hospit alized from Sep. 1996 to Aug. 2004 were randomly divided into case group and con trol group. The case group was injected with somatostain 6 hours before gastrosc ope, while the control group received regular antiacid. [Results] The re-hemorrha ge rates in the case group and the control group were 3.8% and 18% respectively, the difference was significant (t=5 24, P<0.05). Operation rate within short pe riod in the two groups were 1.9% and 13.6% respectively (t=4 84, P<0.05) . The ho spitalization period were (10.1±9.8) days and (16.3±9.2) days respectively ( t= 3.19, P<0.01). Hospitalization fee were (12 362±2 343) yuan and (12 698 ±2 564) yuan respectively (t=0 66, P>0.05). [Conclusion] The case group has obviously l ower re-hemorrhage rate, operation rate and shorter hospitalization period than the control group. No statistic difference was found in the hospitalization fee.