摘要
目的探讨脂肪肝与胰岛素抗性的关系。方法对30例诊断为脂肪肝患者作回顾性分析。结果多数患者合并胰岛素抗性综合征(高血压、肥胖症、糖尿病、高脂血症),18例接受口服葡萄糖耐量试验(OGTT)中,1例确诊为Ⅱ型糖尿病,17例患者中3例空腹血糖减损(IFG),1例糖耐量减退(IGT)及13例糖耐量正常(NGT)具有较正常人为高的血浆胰岛素(INS)浓度,胰岛素抗性脂数为8.91±1.52%。结论脂肪肝与胰岛素抗性所致的代谢紊乱关系紧密,呈正相关系。
Objective To explore fatty live's etiology and its relationship to insulin resistance. M ethods Retrospec-tive review of 30 patients seen over 3 years period. Results The clinical features that define insulin resistance(hypertension, obesity, diabetes and hyperlipidem ia )are com m on in our patients. Of 18 patients underw ent glu-cose tolerance testing. 1 of therm w ere new ly diseased as having diabetes. Seventeen patients(three w ith im pairedfasting glucose.one im paired glucose tolerance,and thirteen norm al glucose tolerance)had exaggerated insulin re-sponses, w ith a insulin resistance index 8.91±1.52% .Conclusion Fatty liver m ay be a sequel of m etabolic distur-bance on the liver due to insulin resistance.
