健身跑对中老年男性激素分泌的影响

Iinfluence of jogging on hormone of the middle aged and elderly

以３０名系统参加健身跑４年以上，每天或隔天坚持锻炼不少于５～６ｋｍ以上，年龄在５０岁以上的男性中老年人作为研究对象，以无器质性心肺疾患，身体健康，无烟酒嗜好，从不参加运动的５０岁以上男性中老年人（２２例）作为对照组。主要测定激素有：生长激素（ｈＧＨ）、促甲状腺释放激素（ＴＳＨ）、促黄体生成激素（ＬＨ）、卵泡刺激激素（ＥＳＨ）及甲状腺素（Ｔ３、Ｔ４）、可的松（Ｃｏｒｔｉｓｏｌ）、胰岛素（Ｉｎｓ）、睾酮（Ｔ）、雌二醇（Ｅ２）及第二信史ｃＡＭＰ、ｃＧＭＰ。各项检测指标均采用放射免疫分析法测定。结果表明，在内分泌系统各层次激素浓度两组之间ＦＳＨ、Ｉｎｓ无显著差异，而ｈＧＨ，ＬＨ，Ｅ２。Ｔ，ＴＳＨ，ＦＴ３，Ｃｏｒｔｉｓｏｌ，ｃＡＭＰ及ｃＧＭＰ水平，健身长跑中老年组有明显变化，两组有非常显著差异（Ｐ＜０．００１），ＦＴ４有显著差异（Ｐ＜０．０５）．提示长期坚持系统健身跑，能使不同层次内分泌功能得到改善与提高，内分泌反馈调节作用得到加强。

Hormones of 30 joggings of middle aged and elderly were studied in comparison with that of control group of 22 cases of middle aged and elderly.The ca es of these two groups were all males.The jogging group aged 53～80,all of them had received physical training for more than 4 years,and consistent training about 5～6km every day or every other day.The control group aged 57一87.None of the 2 groups had history of cardiovascular or respiratory diseases.None of them had any history of drinking or smoking.The main hormones index included:1) Hypothalamic一pituitary axis level:hGH,TSH,LH,FSH.(2) Target glands axis level:T3,T4,cortisol,insulin,E2 T.(3)Second Messenger:cAMP and cGMP. All the hormones are tested by the methods of RIA test. Among them LH,FSH,E2,T FT3,FT4,Ins.,cortisol were tested by methods of CAC; TSH by IRMA; hCH by DPC co. Results of this investigation showed:1) No difference was found on FSH and insulin between these 2 groups.(2)The level of hGH,LH,E T,TSH,FT3.cortisol and,cAMP,cGMP of jogging group were higher increased than that of control group,there were very significant difference between these 2 groups(P<0.001). As for FT4,there was significant difference between these 2 groups(P<0. 05).It is suggested that consistent jogging could improve the function of hormone,feedback regulatory functions,physiological function of varies organs,metabolic regulation,immune functions,health state and hence,prolong life of middle aged and elderly.The mechanism of hormones improving various function were discussed.Author's address:(Renji Hospital Affiliated to Shanghai Second Medical University,Shanghai,200001)