凝胶成型法制备多孔羟基磷灰石生物陶瓷

Preparation of Porous Hydroxyapatite Scaffolds by Combination of the Gel-Casting and Polymer Sponge Methods

介绍了凝胶成型法制备多孔羟基磷灰石支架材料的一种新工艺,通过对浆料配方的设计,保证了浆料的均匀性。利用体视显微镜等对制备的多孔羟基磷灰石孔洞结构进行观察。结果表明:这种方法可以很好地控制多孔支架材料的孔洞结构、大小,孔分布均匀且内部连通,孔径在300～500μm之间。通过改变工艺参数可以控制孔隙率在92%～45%之间变化。对抗压性能的测定结果表明:含HA为50%(质量分数)的陶瓷浆料所得到的多孔体的抗压强度高达5MPa,具有良好的机械性能。

In this paper, a novel technique that integrates the gel-casting technique with polymer sponge method to prepare HA porous scaffolds with improved mechanical strength and controllable porous structure was introduced. The pore morphology, size, and distribution of the scaffolds were characterized using the electron microscope. The scaffolds prepared have an open, uniform and interconnected porous structure with a pore size of 300～500μm. The porosity of the open pores in the scaffold can be controlled in the range of 92%～45%by changing HA concentration.