4-甲基-苯磺酸-2-氧-2-[3-(5-芳基-[1,3,4]噁二唑-2-基)-硫脲]-乙基酯的合成及生物活性研究

Synthesis and Biological Activities of Toluene-4-sulfonic Acid 2-Oxo-2-[3-(5-aryl-[1,3,4]oxadiazol-2-yl)thioureido]ethyl Esters

合成了12个未见文献报道的4-甲基-苯磺酸2-氧-2-[3-(5-芳基-[1,3,4]噁二唑-2-基)-硫脲]-乙基酯,其结构经元素分析、1HNMR和IR确证.初步活性测试结果表明:部分化合物有较好的杀菌活性.

Twelve new toluene-4-sulfonic acid 2-oxo-2-[3-(5-aryl-[1,3,4]oxadiazol-2-yl)thioureido]ethyl esters were synthesized. Their structures were determined by IR, H-1 NMR spectra and elemental analysis. The preliminary biological activity tests show that some of these target compounds have good fungicidal activities.