涎腺粘液表皮样癌术后转移的临床病理因素分析

Study of Clinicopathologic Factors the Postoperative and Metastasis of Mucoepidermoid Carcinoma in Salivary Glands

目的:对经额面外科手术治疗的5 9例涎腺粘液表皮样癌患者进行回顾性研究,分析影响患者术后转移的相关临床病理因素。方法:通过SPSS 10 .0软件分析,筛选出影响涎腺粘液表皮样癌术后转移的主要临床病理因素。结果:粘液表皮样癌低分化,癌巢边界形态为Ⅲ型,镜下坏死患者术后易发生转移。结论:分化程度,癌巢边界形态和镜下坏死是影响术后转移的主要临床病理因素。

Objective: The paraffin slides and clinical documents of 59 cases with mucoepidermoid Carcinomas of Salivary glangs were reviewed, and the correlative clinicopathologic factors influencing the metastasiswere analyzed and the results were expected to be helpful for clinical practice.Methods: The logistic regression model was used to determine the main effective factors. Statistical analysis was performed using the SPSS 10.0 software. Results: The metastasiseasily occured in the cases with poor differentiated tumors, type Ⅲ, necrosis of tumor border and local recurrence. Conclusion: Degree of differentiation patterns of tumor border and necrosis were important factors influencing the postoperative metastasis.