超常剂量谷维素联合溴化普鲁本辛治疗肠易激综合征的疗效观察

Observation on Super-measuring Oryzanol in Association with Propantheline Bromide to Turn the Funtion that Cures IBS

目的:观察超常剂量谷维素联合溴化普鲁本辛治疗肠易激综合征(IBS)的作用。方法:全部患者治疗前停用其它药物,避免刺激性食物摄入,建立合理、规律的生活方式。观察组48例给予谷维素100mg,溴化普鲁本辛15mg,3次/d口服;对照组46例给予复方苯乙哌啶片2片,3次/d口服。服药3周末分别记录疗效情况,以3周末为最终结果。结果:观察组的总有效率为87.5%,对照组的总有效率为56.5%,两组比较疗效具有统计学意义(P<0.05)。结论:两药联合治疗IBS优于传统组方收敛止泻药物治疗,且无明显毒副作用。

Objective: To observe super-measuring oryzanol in association with propantheline bromide to turn the function that cures IBS. Method: All suffers stop using the other medicine before the treatment, avoid the stimulating food and establish the reasonable and regulate life style. The 48 observed examples were given oryzanol 100mg and propantheline bromide 15mg ,taking orally 3 times every day.The 46 matched examples are Diphenoxylate Co. 2 pills ,taking orally 3 times every day. A medicine in 3 weekend record the treatment circumstance, With 3 weekends being final result. Result : The observed group has gross efficiently for 87.5%, the matched group for 56.5%. Two comparisons of the curative effection have the covariance meaning (P<0.05) .Conclusion:Two medicine in association with the treatment IBS surpass the traditional square refrains from the rash action of relieve diarrhea and they have no obvious side effect.