RANKL/OPG与人多发性骨髓瘤骨病的关系
摘要
多发性骨髓瘤(MM)是以骨髓微环境中浆细胞恶性增殖为特征的血液肿瘤。细胞核因子κB受体活化因子配基(RANKL) /护骨素(OPG)与MM发病关系密切。在MM中,存在RANKL表达上调、OPG表达下调;这种RANKL/OPG比率异常与MM骨病及骨病范围、MM的肿瘤负荷、分期和预后均有关。
出处
《国外医学（生理病理科学与临床分册）》
2005年第2期151-152,共2页
Foreign Medical Sciences(Pathophysiology and Clinical Medicine)
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