控制快速房性心律失常心室率即时疗效临床用药体会

Efficacy and safety of intravenous cediland and esmolol and daltiazem for controlling rapid atrial arrhythmias.

目的观察并比较静脉注射毛花甙C、艾司洛尔及地尔硫(艹卓)控制快速房性心律失常心室率的有效性.方法将2001-03～2003-08中国医学科学院阜外心血管病医院94例快速房性心律失常(房颤、房扑、房速)患者随机分为3组,分别静脉用毛花甙C(29例)、艾司洛尔(30例)和地尔硫(艹卓)(35例).结果毛花甙C、艾司洛尔和地尔硫(艹卓)均能有效控制快速房性心律失常的心室率,心室率下降幅度分别为30.4%、29.3%和27.6%,总有效率分别为86%、83%和85%,平均用药有效时间分别为(34.3±21.0)min、(10.0±3.9)min和(10.0±3.9)min.结论艾司洛尔、毛花甙C及地尔硫(艹卓)均能有效、迅速、安全控制快速房性心律失常的心室率.

ObjectiveTo evaluate the efficacy of intravenous cediland(lanatoside C) and esmolol and daltiazem for controlling rapid atrial arrhythmias.MethodsA total of 94 patients with rapid atrial arrhythmias were randomized to receive intravenous cediland(n=29) and esmolol(n=30) and daltiazem(n=35),respectively.ResultThe total efficacy rate were 86%,83% and 85%,with a mean decrease in heart rate by 30.4%,29.3 and 27.6% compared to baseline,and mean response times was 34.3±21.0min、8.1±2.1min and 11.3±3.8min,respectively.ConclusionThree drugs are all effective、rapid and safe in slowing rapid ventricular rate in patients with rapid atrial arrhythmias.