干预后脑卒中死亡率的变化（1986～1990）──中国七城市脑卒中危险因素干预试验

CHANGES 0F STHOKE MORTALITY AFTER IN-TEEVENTION TRIALL一RESULTS OF AN INTER-VENTION TRIAL OF STROKE RISK FACTORSIN 7 CITIES OF THE EOPLE ′S REPUBLIC OF CHINA

本文对我国七个城市的社区人群和定群研究样本进行干预前后脑卒中死亡率的变化进行分析，并对干预与非干预两组结果进行比较。结果表明①干预社区人群（Ａ）脑卒中死亡率在１９９０年比１９８６年明显下降，而对照非干预人群（Ｂ）基本上无变化；②定群样本中干预组与对照组，包括各亚组之间的对比，前者脑卒中死亡率的下降明显大于后者，且有统计学显著性差异；按男女性别分，无论是干预社区人群（Ａ）或对照社区人群（Ｂ）以内，男性与女性间无显著性差异，而在干预与对照组之间比较，无论男性或女性其差异均有显著性。

he study is a primary prevention trial in 7 citiesoft he People′s Republic of Cina to test the effect of multi- factor intervention ,consisting of drug and non-drug thera-py for hypertension and health education to enhance self- health一care of Whole community population onstorke. T hetotal sample consisted 11 5, 065 individuals, among them 57. 151 w ere in the intervention communities、(A)and 57,911 in the control communities (B ),I n January I 1 988,when 7 cities began the trial simultaneously,there were 36. 919 individuals in the cohort.among which 18, 108 individ-uals and 18.511 individu als were in the intcrvention group(CA )and control group(CB)respectively . At the end ofthe trial, Aand B w ere monitored4 years; CA and CB and their subgroups were followed-up for3years.Them ain results were as fo llow:(1)In contrast with B,the strode nortality of A in 1990 decreased obviously ; (2)Incomparison withCB (induding its subgroups ),the person-year m ortdlity of strokein CA(including its subgroups)de-clined significantly;and(3)there were also a significantdi fference in m ale or fem ale in the comparison of A and B.