重症肺炎患儿内环境紊乱的临床研究

Clinical Study of Internal Milieu Disorder in The Severe Pneum onia

目的:探讨重症肺炎患儿内环境紊乱的情况及与病情发展的关系。方法:对2 0 0 2年10月～2 0 0 4年3月包头市第四医院儿科住院的78例重症肺炎患儿急性期进行血糖、血钾、钠、钙的检测,并与同期32例普通支气管肺炎患儿为对照组进行比较,行统计学分析。结果:重症肺炎急性期时,患儿有内环境紊乱发生,以高血糖、高血钾、低血钠、低血钙为主,且血糖、血钾的平均值高于对照组,而血钠、血钙平均值低于对照组,有显著性差别。结论:重症肺炎急性期时,患儿处于应激状态,存在应激损伤,可引起应激性高血糖及电解质紊乱,加重病情。提示在病情急性期应控制过度应激反应,稳定内环境,有利于病情恢复。

Objective:To discuss the relationship be tw een the internal milieu disorder and the development of condition in severe pneu monia.Methods:From October 2002 to March 2004,78 hospitalized ch ildren with severe pneumonia were included.The level of blood glucose,serum pota s sium,natrium and calcium were detected and compared with those of 32 children wi th bronchopneumonia.The results were statistically analyzed.Results: In acute stage of severe pneumonia,the internal milieu was disordered,showin g higher levels of blood glucose and serum potassium and lower levels of serum n atrium and calcium than that of controls.The difference was significant. Conclusion:In acute stage of severe pneumonia,cases is in stringent stat e,which induces increasing in blood glucose and electrolyte imbalance.It indicat es that controlling excessive stress reaction and balancing internal milieu in a cute stage of severe pneumonia is helpful to recovery.