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共刺激通路阻断剂在角膜移植排斥治疗中的应用 被引量:1

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摘要 共刺激通路阻断剂是利用分子生物学方法重组免疫调节分子,人为干预免疫应答,以抑制特异性T细胞免疫反应,在诱导移植耐受和治疗自身免疫性疾病中显示了良好的应用前景。本文针对角膜组织的免疫学特点及共刺激通路阻断剂如CTLA4 Ig、CD4 0Ig、抗CD15 4mAb、CTLA4 FasL在角膜移植排斥治疗中的应用进行综述。
作者 陈敏 史伟云
出处 《国外医学(眼科学分册)》 2005年第2期76-79,共4页 Foreign Medical Sciences(Section of Ophthalmology )
基金 国家自然科学基金资助项目 (3 0 2 712 3 9)
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