ZAP-70在慢性淋巴细胞白血病中的表达及意义
摘要
慢性淋巴细胞白血病是预后异质性很大的疾病。ZAP-70是一种蛋白酪氨酸激酶,在约50% B-CLL表达,与IgVH基因突变、细胞遗传学改变和CD38有明显相关性,已被作为一项独立预后指标,对临床指导治疗有重要价值。
出处
《国外医学(输血及血液学分册)》
2005年第3期216-218,共3页
Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
基金
基金项目:江苏省"135工程"医学重点人才基金资助项目(RC2002044)
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