摘要
异基因造血干细胞移植是治疗恶性血液病最有效的手段之一,但人类白细胞抗原(HLA)屏障限制了其广泛应用。随着免疫学、分子生物学、细胞生物学理论和技术的不断发展,HLA半相合造血干细胞移植日益受到关注。本文就其研究进展作一综述。
出处
《国外医学(输血及血液学分册)》
2005年第3期241-244,共4页
Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
二级参考文献13
-
1Slavin S,Ackerstein A,Naparstek E,et al.The graft-versus-leukemia (GVL) phenomenon:is GVL separable from GVHD? Bone Marrow Transplantation,1990,6:155-161.
-
2Amlot PL,Rawlings E,Fernando ON,et al.Prolonged action of a chimeric interleukin-2 receptor(CD25) monoclonal antibody used in cadaveric renal transplantation.Transplantation,1995,60:748-755.
-
3Baker MB,Altman NH,Podack ER,et al.The role of cell-mediated cytotoxicity in acute GVHD after MHC-mediated bone marrow transplantation in mice.J Exp Med,1996,183:2645-2656.
-
4Harris DT,Sakiestewa D,Lyons C,et al.Prevention of graft-versus-host disease (GVHD) by elimination of recipient-reactive donor T cells with recombinant toxins that target the interleukin2 (IL-2) receptor.Bone Marrow Transplantation,1999,23:137-144.
-
5Montagna D,Yvon E,Calcaterra V,et al.Depletion of alloreactive T cells by a specific anti-interleukin-2 receptor P55 chain immuotoxin dose not impair in vitro antileukemia and antiviral activity.Blood,1999,93:550-556.
-
6Fleming DR,Henslee-Downey PJ,Romond EH,et al.Allogeneic bone marrow transplantation with T-cell depleted partially matched related donors for advanced acute lymphblastic leukemia in children and adults:a comparative matched cohort study.Bone Marrow Transp
-
7Goldman FD,Rumelhart SL,Dealacron P,et al.Poor outcome in children with refractory/relapsed leukemia undergoing bone marrow transplantation with mismatched family member donors.Bone Marrow Transplantation,2000,25:943-948.
-
8Przepiorka D,Weisdorf D,Martin P,et al.Consensus conference on acute GVHD grading.Bone Marrow Transplantation,1995,15:825-828.
-
9Vowels MR,Honeyman M,Ziegler J,et al.Searches for matched and closely matched related and unrelated marrow donors undertaken in paediatric unin.J Pediatr Child Health,1992,28:379-382.
-
10Beatty PC,Clift RA,Mickelson EM,et al.Marrow transplantation from related donors other than HLA-identical siblings.N Engl J Med,1985,313:765-771.
共引文献7
-
1郭智,陈惠仁,刘晓东,楼金星,杨凯,陈鹏.单倍型造血干细胞移植治疗幼年型粒单核细胞白血病的临床研究[J].发育医学电子杂志,2014,2(3):150-154. 被引量:6
-
2龙卉,唐锁勤,张晓飞.化学修饰物甲氧基聚乙二醇对异基因骨髓移植影响的研究[J].中国实验血液学杂志,2005,13(3):408-411.
-
3王三斌,郭坤元,胡灯明,尹波,彭利晖,刘林.HLA不全相合异基因外周血干细胞移植治疗重型再生障碍性贫血[J].解放军医学杂志,2006,31(5):484-485. 被引量:2
-
4张建华.骨髓采集术麻醉方法的选择[J].中国组织工程研究与临床康复,2007,11(28):5634-5635. 被引量:1
-
5马海燕,李向红,李红,张采欣,徐风森.孕期不同阶段铅暴露时大鼠胎盘基质金属蛋白酶-9及组织抑制剂-1的表达[J].国际儿科学杂志,2008,35(3):199-201. 被引量:1
-
6陈惠仁,何学鹏,司英健,胡波,杨凯,杜振兰,张小妹.单体型造血干细胞移植治疗儿童白血病研究进展[J].国际儿科学杂志,2008,35(3):293-294. 被引量:1
-
7郭智,陈惠仁,何学鹏,刘晓东,杨凯,陈鹏,刘丹,张媛,楼金星.单倍型异基因造血干细胞移植治疗儿童难治性或复发白血病30例[J].中华器官移植杂志,2013,34(1):33-36. 被引量:16
同被引文献18
-
1黄晓军,刘代红.人类白细胞抗原不合或单倍体亲属供者造血干细胞移植[J].临床内科杂志,2006,23(9):581-584. 被引量:17
-
2曹永彬,王健民,解琳娜,江千里,高磊,邱慧颖,周虹.粒细胞集落刺激因子联用激素和(或)免疫抑制剂动员供体小鼠外周血造血干细胞对其免疫系统的影响[J].第二军医大学学报,2006,27(11):1200-1203. 被引量:1
-
3梁旭,黄晓军.rhG-CSF未经动员与动员后供者外周血淋巴细胞与干细胞采集物的细胞构成及功能比较[J].中华内科杂志,2007,46(7):566-568. 被引量:6
-
4Purton JF, Monk JA, Liddicoat DR, et al. Expression of the glucocorticoid receptor from the 1 A promoter correlates with T lymphocyte sensitivity to glucocorticoid-induced cell death. J Immunol, 2004, 173: 3816-3824.
-
5Ling Y, Cao X, Yu Z, et al. Circulating dendritic cells subsets and CD4 + Foxp3 + regulatory T cells in adult patients with chronic ITP before and after treatment with high-dose dexamethasome. Eur J Haematol, 2007,79 : 310 -316.
-
6Chen X, Murakami T, Oppenheim J, et al. Differential response of murine CD4 + CD25 + and CIM + CD25 - T cells to dexamethasane-induced cell death. Eur J Immunol,2004,34:859-869.
-
7Butts CL, Shukair SA, Duncan KM, et al. Effects of dexamethasone on rat dendritic cell function. Horm Metab Res, 2007,39: 404-412.
-
8Piemonti L,Monti P,Allavena P, et al. Glucecorticoids affect human dendritic cell differentiation and maturation. J Immunol, 1999, 162:6473-6481.
-
9Matasic R, Dietz AB, Vuk-Pavlovic S. Dexamethasone inhibits dendritic cell maturation by redirecting differentiation of a subset of cells. J Leukoc Biol, 1999,66:909-914.
-
10Dey BR, Spitzer TR. Current status of haploidentical stem cell transplantation. Br J Haematol,2006 ,135 :423-437.
-
1周凡,刘丽梅,刘彦琴,张雪梅,郭步云,朴英.HLA半相合造血干细胞移植后移植物抗宿主病的预防[J].沈阳部队医药,2003,16(4):316-318.
-
2李登举,张东华,黄伟,肖毅,孟凡凯,周剑锋,刘文励.HLA半相合造血干细胞移植治疗难治性白血病二例[J].中华器官移植杂志,2006,27(7):437-438.
-
3张勇,倪旭东,秦贤举,吴铮,陈问潭,李文如,赵大方,赵纲,张华,成剑文.乳腺癌保乳手术相关技术的探讨[J].中华医学杂志,2003,83(19):1712-1713. 被引量:8
-
4朱玉兰.乳腺癌综合治疗的探讨(附320例临床分析)[J].江苏大学学报(医学版),2003,13(5):436-437. 被引量:1
-
5苏毅,易海,赖思含,范方毅,付利,何光翠,刘一岚,侯严堂,孙浩平,王译,邱玲,缪晓娟,李业成.荷载自体白血病抗原的HLA半相合DC-CIK联合CAG方案治疗老年AML[J].中国输血杂志,2013,26(11):1080-1083. 被引量:4
-
6李英俊,孙玉兰.Ⅰ、Ⅱ期乳腺癌保乳手术治疗31例临床分析[J].社区医学杂志,2006,4(10S):76-77.
-
7文钦,张曦,陈幸华,高蕾,张诚,高力,王庆余.父供女HLA半相合造血干细胞移植后供者DC-CIK细胞输注治疗儿童难治复发性急性髓细胞白血病1例并文献复习[J].重庆医学,2010,39(14):1852-1853. 被引量:4
-
8姜军.乳腺癌内乳淋巴结转移的诊治进展[J].中国实用外科杂志,2006,26(4):265-267. 被引量:7
-
9杨光.HLA半相合造血干细胞移植在儿科应用的研究进展[J].国外医学(儿科学分册),2002,29(2):79-82. 被引量:2
-
10王存邦,欧英贤,达万明,白海.自体外周血干细胞混合HLA半相合异体骨髓移植治疗多发性骨髓瘤[J].临床血液学杂志,2002,15(6):272-273.