摘要
肝素诱导的血小板减少症是一种药物诱导的血小板减少症,伴有抗体反应和血栓形成,是临床使用肝素所引起的一种严重的并发症。本文综述该疾病的发病率及诊断、高凝状态的原因及防治进展。
出处
《国外医学(输血及血液学分册)》
2005年第3期253-256,共4页
Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
参考文献22
-
1Warkentin TE, Roberts RS, Hirsh J, et al. An improved definition of immune heparin-induced thrombocytopenia in postoperative orthopedic patients. Arch Intern Med, 2003, 163(20):2514-2518.
-
2Council for International Organization of Medical Sciences (CIOMS).Benefit-risk balance for marketed drugs: evaluating safety signals. The Report of CIOMS Working Party Ⅳ, Geneva, Switzerland, 1998.
-
3Warkentin TE, Kelton JG. Delayed-onset Heparin- induced thrombocytopenia and thrombosis. Ann Intern Med, 2001, 135(11):502-506.
-
4Eichler P, Kroll H, Greinacher A. A comparison of denaparoid and lepirudin in Heparin- induced thrombocytopenia. Thromb Haemost, 2001, 85(6):950-957.
-
5Greinacher A, Eicher P, lubenow N, et al. Heparin- induced thrombocytopenia with thromboembolic complications: meta-analysis of 2 prospective trials to assess the value of parenteral treatment with lepirudin and its therapeutic aPTT range. Blood,2000, 96(3):846-851.
-
6Lewis BE, Wallis DE, Berkowitz SD, et al. Argatroban anticoagulant therapy in patients with Heparin- induced thrombocytopenia. Circulation, 2001, 103(14):1838-1843.
-
7Lewis BE, Wallis DE, Leya F, et al. Argatroban anticoagulation in patients with Heparin- induced thrombocytopenia. Arch Intern Med, 2003, 163(15):1849-1856.
-
8Warkentin TE. Heparin- induced thrombocytopenia, part 2; clinical course and treatment. J Crit Illn, 2002, 360(1):491.
-
9Warkentin TE, Kelton JG.A 14-year study of Heparin- induced thrombocytopenia. Am J Med,1996, 56(5):12-16.
-
10Wallis DE, Workman DL, Lewis BE, et al. Failure of early heparin cessation as treatment for Heparin- induced thrombocytopenia. Am J Med, 1999,106(6):629-635.
同被引文献83
-
1季闽春,钱庆庆,杨耀芳.肝素诱导的血小板减少症的病因、诊断和治疗研究进展[J].中国临床药理学杂志,2007,23(6):461-465. 被引量:21
-
2杜振宗.体外循环中肝素诱导血小板减少症的诊断和处理[J].北京医学,2005,27(7):441-443. 被引量:2
-
3熊长明,何建国,柳志红,程显声.肝素诱导血小板减少症1例[J].实用医学杂志,2005,21(15):1727-1727. 被引量:2
-
4林乐文,李雪艳,周承孝.肝素诱发血小板减少症与有关体外循环抗凝问题[J].中国体外循环杂志,2005,3(3):187-189. 被引量:6
-
5Keeling D,Davidson S,Watson H,曹丽娟(编译),王兆钺(审校).肝素诱发的血小板减少治疗指南[J].国际输血及血液学杂志,2006,29(6):545-549. 被引量:5
-
6Warkentin TE, Chong BH, Greinacher A. Heparin induced thrombocytopenia: toward consensus[J]. Thromb Haemost, 1998, 79:1-7.
-
7Chong BH, Castaldi PA. Platelet proaggregating effects of heparin: possible mechanism for non-immune heparin associated thrombocytopenia[J]. Aust NZ J Med, 1986,16:715- 716.
-
8Gurbuz AT, Elliott WG, Zia AA. Heparin induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines[J]. Eur J Cardiothorac Surg ,2005, 27:138-149.
-
9Arnold DM, Kelton JG. Heparin-induced thrombocytopenia: an iceberg rising[J]. Mayo Clin Proc, 2005,80:988-990.
-
10Suvarna S, RauovaL, McCrackenEK, et al. PF4/heparin complexes are T cell-dependent antigens[J]. Blood, 2005,106: 929-931.
引证文献10
-
1付宇,王丹,袁莉,石鹏,赵武,林为民.普通肝素致血液透析患者血小板减少20例[J].第四军医大学学报,2007,28(2):110-110. 被引量:2
-
2常增义,张永红.普通肝素致血液透析患者血小板减少23例分析[J].中国误诊学杂志,2008,8(1):207-208. 被引量:1
-
3曹磊,谭颖,吕继成,喻陆,赵明辉.肝素诱导的血小板减少症[J].中国血液净化,2009,8(3):163-166. 被引量:16
-
4田红燕,孟燕,张军波,马强,成革胜,范粉灵,王军,万红梅.肝素诱导的血小板减少症的临床观察[J].中华医学杂志,2009,89(20):1405-1407. 被引量:10
-
5田玉龙,张曦彤.下肢深静脉血栓介入治疗发生肝素诱发血小板减少伴血栓形成综合征一例[J].介入放射学杂志,2012,21(1):53-54. 被引量:9
-
6侯雪平,裴斐.低分子肝素致血小板减少症一例分析[J].实用药物与临床,2012,15(2):99-100. 被引量:4
-
7沈珠,曹国文,张全英,施爱明,曹斌,杨文斌.肝素和利奈唑胺致冠心病PCI术后严重血小板减少1例分析[J].中国药房,2012,23(12):1118-1120. 被引量:2
-
8范思佳,高会远,张永飞,陈丽娟.冠状动脉粥样硬化PCI术后肝素诱导血小板减少症的诊治[J].中国实验诊断学,2014,18(10):1731-1733. 被引量:2
-
9赵明,李向东,李毅,沈海燕,翟英,周麟.维持性血液透析患者肝素诱导的血小板减少症的临床观察[J].临床肾脏病杂志,2014,0(12):730-733. 被引量:5
-
10成昌娟,杨忠慧,陈国梅,胡旻昊,孙洁.低分子肝素钙和万古霉素致一患者骨科术后严重血小板减少[J].药学与临床研究,2017,25(1):73-74. 被引量:1
二级引证文献52
-
1马力,阎军,王培红,张强,何毅刚,刘龙,闫盛.维持性血液透析出现肝素诱导血小板减少症1例[J].血管与腔内血管外科杂志,2020(5):463-466.
-
2赵继红,田洁,王冰月,袁平.维持性血液透析患者并发脑出血的临床分析[J].天津医药,2009,37(9):798-799. 被引量:5
-
3丁生辉,雷招宝.药源性血小板减少症及其防治[J].海峡药学,2010,22(2):91-94. 被引量:26
-
4钟红霞,许荣方,杨志明.尿毒症维持性血透患者并发脑出血的临床分析[J].浙江临床医学,2010,12(6):599-600. 被引量:9
-
5何文梅.组合型人工肾治疗头孢菌素致尿毒症脑病10例的护理[J].中国误诊学杂志,2010,10(32):7944-7945. 被引量:1
-
6汪宏,姚永兴,方靖,刘鲲.尿毒症维持性透析患者死亡原因分析及对策[J].安徽医药,2011,15(10):1255-1256. 被引量:10
-
7胡会社,王崇宝,马庆久.阿加曲班在肝素诱发血小板减少症的应用[J].血栓与止血学,2011,17(5):224-225. 被引量:3
-
8李昭辉,徐益鸣,洪诗钗,杨东海,刘青.阿加曲班治疗肝素诱导血小板减少症二例[J].中华普通外科杂志,2011,26(12):997-997.
-
9蒋兰萍,陈丽萌.从血液透析的角度看肝素诱导的血小板减少症[J].中国血液净化,2011,10(12):681-685. 被引量:9
-
10尹霞.肝素诱导血小板减少症1例的治疗体会[J].中国医疗前沿,2011,6(24):42-42. 被引量:4
-
1董梅,葛培培,张真真,李留东.肝素诱导的血小板减少症一例[J].中国循环杂志,2015,30(5):504-504.
-
2陈韵岱,陈华.冠状动脉介入术后肝素诱导的血小板减少症治疗一例[J].中华医学杂志,2005,85(44):3161-3162. 被引量:3
-
3邓建丽.肝素诱导的血小板减少症致急性心梗1例[J].中国冶金工业医学杂志,2013,30(3):271-271.
-
4陈华,陈韵岱.冠状动脉介入术后肝素诱导的血小板减少症1例[J].心肺血管病杂志,2006,25(3):137-137. 被引量:1
-
5吕宏,王玉娟,廖海鲲,田文庆,袁红.肝素诱导的血小板减少症一例诊治经验教训[J].中国介入心脏病学杂志,2009,17(4):230-231. 被引量:2
-
6申玉静,杨跃进.肝素诱导的血小板减少症诊断与治疗[J].中华心血管病杂志,2009,37(4):381-384. 被引量:24
-
7许剑辉,杨仁池.肝素诱导的血小板减少症临床诊断和治疗进展[J].中华血液学杂志,2010,31(3):204-207. 被引量:10
-
8赵园媛.1例肝素诱导的血小板减少症患者的观察和护理体会[J].中国中西医结合急救杂志,2013,20(3):164-164.
-
9曾庆为,谢华,郑岩,马壮.低分子肝素诱导的血小板减少症2例并文献复习[J].临床肺科杂志,2012,17(5):962-962. 被引量:5
-
10董岸莺,马兴杰,韩国华.低分子肝素诱导血小板减少症1例[J].重庆医学,2013,42(32):3976-3976. 被引量:1