摘要
目的探讨原发嗜酸细胞增多症的临床特点。方法回顾性分析55例原发嗜酸细胞增多症患者的临床资料。结果55例均符合原发嗜酸细胞增多症的诊断标准,男性为女性的2倍。胃肠道异常为最常见的临床表现(50.8%),其次为肺部病变(37.7%)、心脏病变(26.2%)和神经系统病变(21.3%);其他临床表现包括皮肤改变(19.7%)、浅表淋巴结肿大(18%)、血栓形成(9.8%)和哮喘(3.3%)。肠黏膜和浅表淋巴结活检均表现为大量嗜酸细胞浸润,经糖皮质激素治疗后临床表现均明显好转。结论男性较女性更易患原发嗜酸细胞增多症,最常见的受累器官为胃肠道、肺、心脏和神经系统,糖皮质激素治疗有效。
Objective To retrospectively analyze the clinical features of idiophathic hypereosinophilia patients admitted to Peking Union Medical College Hospital during 1983 to 2003. Methods The clinical manifestations of 55 patients with idio phathic hypereosinophilia were reviewed retrospectively. Results Among 55 patients with idiopathic hypereosinophilia, men were 2 times more than women. The most common involved organs were gastrointestine (50.8%), lung (37.7%), heart (26.2%) and nervous system (21.3%). Skin (19.7%), superficial lymph nodes involvement (18%), thrombosis (9.8%) and asthma(3.3%) could also be observed. The gastrointestinal mucosa and lymph node biopsy had demonstrated massive eosinophil infiltration. The eosinophil count and clinical manifestations responsed well to corticosteroid treatment. Conclusions Male are more precipitate to have hypereosinopkilia than female patients. The most frequently involved organs are gastrointestinal tract, lung, heart and nervous system. corticosteroid is very effective.
出处
《北京医学》
CAS
2005年第4期225-227,共3页
Beijing Medical Journal