摘要
以微晶纤维素和(3,5-二甲基)苯基异氰酸酯为原料合成了纤维素-三(3,5-二甲基苯基氨基甲酸酯),经红外光谱和元素分析知微晶纤维素已酯化完全.用不同的方法(沉积法和蒸发法)将其涂敷于氨基丙烷化硅胶上制得了纤维素-三(3,5-二甲基苯基氨基甲酸酯)手性柱,对柱进行了评价,并在正己烷-异丙醇(体积比为90∶10)为流动相,流速为1.0mL·min-1,柱温25℃下拆分了几种手性物质.
Cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC) were synthesized by the reaction of micrystalline cellulose with 3,5-dimethylphenylisocyanate in dry pyridine at 110℃. Elemental analysis and IR spectra indicated that most of the hydroxy groups of the microcrystalline cellulose had been converted into ester (groups. The) chiral stationary phases(CSP) were prepared by coating cellulose tris (3,5-dimethylphenylcarbamate) on the aminopyopyl silica. The evaluation of column was achieved hexane/2-propanol (90∶10 volume ratio) as mobile phase at a flow rate of 1mL·min^(-1) (at 25℃). And the results of the separation of chiral compound showed that the chiral stationary has good steroelectivity.
出处
《河南科学》
2005年第3期352-355,共4页
Henan Science
基金
国家自然科学基金资助项目(30160092)
