摘要
聚乙二醇氰乙酸酯和十六烷基氰乙酸酯聚合得到两亲性的标题聚合物,通过IR、1HNMR及凝胶渗透色谱法等确证结构。将此聚合物用溶剂-非溶剂法所制得的纳米粒粒径为100～400nm,分布均匀。
The title copolymer was synthesized by condensing methoxypolyethylene glycol cyanoacetate withhexadecyl cyanoacetate, and its structure was validated by Fourier transform infrared spectrometry, nuclear magnetic reso-nance and gel permeation chromatography. The diameters of the nanoparticles prepared by solvent-nonsolvent method usingtitle copolymer were in the range of 100 - 400nm with a uniform distribution.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
2005年第3期152-155,共4页
Chinese Journal of Pharmaceuticals
基金
上海市科技发展基金(0243nm067)
关键词
聚乙二醇-聚十六烷基氰丙烯酸酯
制备
纳米粒
中间体
poly (PEG cyanoacrylate-co-hexadecyl cyanoacrylate)
preparation
nanoparticle
intermediate
