摘要
采用不同溶剂提取了三七的不同部位,即提取三七皮和芯的化学成分,通过研究提取液的紫外 可见光谱(UV- Vis) ,傅里叶变换红外光谱(FTIR)、荧光光谱(FS)、电喷雾离子质谱(ESI -MS)及高效液相色谱(HPLC) ,寻找谱学特征与其化学成分的相关性,从化学成分的角度解释了三七皮与芯的药理效应差异的可能原因。
Notoginseng (Sanqi) is one of the most important components of famous Chinese recipe (Yunan Baiyao) and possesses a wide variety of applications in clinical practice. It has been found that Sanqi of different size exhibits different curative effects. Such a phenomenon may be attributed to that the chemical constituent from shell region is different from that of core region. To prove the above-mentioned hypothesis, Ultraviolet-Visible (UV-Vis), FTIR, fluorescence spectroscopy, together with high performance liquid chromatography (HPLC) and electrospray ionization mass spectroscopy (ESI-MS) were utilized to study the variation of chemical compositions from shell and core regions of Sanqi. The results demonstrate that the chemical compositions of Sanqi from shell and core regions are different. In summary, differences in chemical composition between Sanqi shell and core were manifested from versatile aspects. Such differences shed a light on the different curative effects of Sanqi.
出处
《光谱学与光谱分析》
SCIE
EI
CAS
CSCD
北大核心
2005年第4期579-583,共5页
Spectroscopy and Spectral Analysis
基金
国家重点基础研究发展规划项目 (G1 9980 61 30 7)
国家自然科学基金 (50 2 0 30 0 1
2 0 1 71 0 0 4 )
科技部极端条件下物质的标准(2 0 0 2CCA0 1 90 0 )
北京大学中药现代研究中心基金 (2 0 1 0xc)资助项目