广西黑衣壮族中老年人群高脂血症患病率调查

A prevalence survey of hyperlipidemia in the middle-aged and elderly people in Guangxi Hei Yi Zhuang population

目的了解广西黑衣壮族中老年人群高脂血症的患病情况。方法采用整群抽样方法对657例黑衣壮族中老年人进行血压、身高、体重、体质指数、血脂及载脂蛋白测定,并将其结果与520例当地的汉族中老年人作比较。结果黑衣壮族和汉族人群高胆固醇血症、高甘油三酯血症及高脂血症的患病率分别为289%和358%(P<005)、132%和167%(P>005)及362%和423%(P<005)。黑衣壮族和汉族人群高高密度脂蛋白胆固醇、高低密度脂蛋白胆固醇、高载脂蛋白B、高载脂蛋白A1/载脂蛋白B比值及低载脂蛋白A1的患病率分别为737%和683%(P<005)、117%和177%(P<001)、123%和204%(P<001)、49%和19%(P<001)和03%和06%(P>005)。结论黑衣壮族较汉族人群高脂血症的患病率低,这可能与他们的饮食习惯、生活方式、体力活动以及遗传背景不同有关。

Objective To investigate the prevalence rate of hyperlipidemia in the middle-aged and elderly in Guangxi Hei Yi Zhuang population. Methods A total of 657 people of Hei Yi Zhuang nationality aged 40 years and over were surveyed. Blood pressure, body height, body weight, serum lipid and apolipoprotein levels were measured, and both body surface areas and body mass index were calculated. The results were compared with those in 520 people of Han nationality who also live in that district. Results The prevalence of hypercholesterolemia, hypertriglyceridemia, and hyperlipidemia in Hei Yi Zhuang vs. Han population were 28.9% vs. 35.8%(P<0.05), 13.2% vs. 16.7% (P>0.05), and 36.2% vs. 42.3%(P<0.05) respectively. Increased rates of high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, apolipoprotein B (apo B), and the ratio of apolipoprotein A1 (apo A1) to apo B, and decreased rate of apo A1 in Hei Yi Zhuang nationality vs. Han nationality were 73.7% vs 68.3% (P<0.05), 11.7% vs. 17.7% (P<0.01), 12.3% vs 20.4% (P<0.05), 4.9% vs. 1.9% (P<0.01), and 0.3% vs 0.6% (P>0.05) respectively. Conclusions Prevalence of hyperlipidemia of Hei Yi Zhuang is lower than that of Han ethnic group, which might results from different dietary habit, life style, physical activity, and even genetic background.