脂多糖对抗原提呈细胞作用的影响
摘要
脂多糖的免疫调节效应能辅助机体的细胞免疫和体液免疫,促进机体的抗感染能力,但是大多数细菌脂多糖同时还有强的毒性作用,引起机体病理损伤。因此,了解脂多糖在免疫应答的重要环节——抗原提呈中的作用及其机制,对开发LPS的临床应用是非常重要的。
出处
《国外医学(免疫学分册)》
2005年第3期166-169,共4页
Foreign Medical Sciences(Section of Immunology Foreign Medical Sciences)
参考文献20
-
1Schromm AB, et al. Biological activities of lipopolysaccharides are determined by the shape of their lipid A portion[J] .Eur J Biochem, 2000, 267(7) :2008-2013.
-
2Lukasiewicz J, Lugowski C. Biologic activity of lipopolysaccharides [ J ].Postepy Hig Med Dosw, 2003,57(1 ): 33-53.
-
3Carswell EA, et al. An endotoxin-induced serum factor that causes necrosis of tumors[J]. Proc Natl Acad Sci USA, 1975,72(9):3666-3670.
-
4王启辉,冷静,王健,郑禹.LPSp作为乙型肝炎表面抗原佐剂的初步研究[J].广西预防医学,2004,10(5):257-259. 被引量:1
-
5Alexander C, Rietschel ET. Bacterial lipopolysaccharides and innate immunity[J] .J Endotoxin Res,2001,7(3): 167-202.
-
6Muta T,Takeshige K. Essential roles of CD14 and lipopolysaccharide-binding protein for activation of toll-like receptor (TLR)2 as well as TLR4 Reconstitution of TLR2- and TLR4-activation by distinguishable ligands in LPS preparations[J]. Eur J Biochem,2001,268(16) :4580-4589.
-
7Su GL, et al. Kupffer cell activation by lipopolysaccharide in rats: role for lipopolysaccharide binding protein and toll-like receptor 4[J]. Hepatology,2000,31 (4): 932-936.
-
8Wizemann TM, Laskin DL. Enhanced phagocytosis, chemotaxis, and production of reactive oxygen intermediates by interstitial lung macrophages following acute endotoxemia[J]. Am J Respir Cell Mol Biol, 1994,11 (3):358-365.
-
9Frevert CW, et al. The effect of endotoxin on in vivo rat alveolar macrophage phagocytosis[ J]. Exp Lung Res, 1998.24(6) :745-758.
-
10Cramer LA, Nelson SL, Klemsz MJ. Synergistic induction of the Tap-1 gene by IFN-gamma and lipopolysaccharide in macrophages is regulated by STAT1[ J]. J Immunol,2000,165(6) :3190-3197.
二级参考文献11
-
1Nishizawa T, Inagawa H, Oshima H, et al. Homeostasis as regulated by activated macrophage. I. Lipopolysaccharide (LPS) from wheat flour: isolation, purification and some biological activities[J]. Chem Pharm Bull (Tokyo), 1992, 40(2): 479-483.
-
2Johnson AG, Gaines S,Landy M. Studies on the O antigen of Salmonella typhosa. V. Enhancement of antibody response to protein antigens by the purified lipopolysaccharide[J]. J Exp Med, 1956, 103(2): 225-246.
-
3Johnson DA, Keegan DS, Sowell CG, et al. 3-O-Desacyl monophosphoryl lipid A derivatives: synthesis and immunostimulant activities[J].J Med Chem, 1999, 42(22): 4640-4649.
-
4Mizuno D, Soma G. Oral or percutaneous administration of lipopolysaccharide of small molecular size may cure various intractable diseases: a new version of Coley's toxin[J]. Mol Biother, 1992, 4(4): 166-169.
-
5Okutomi T, Nishizawa T, Inagawa H, et al. Inhibition of morphine dependence by a lipopolysaccharide from Pantoea agglomerans[J]. Eur Cytokine Netw, 1992, 3(4): 417-420.
-
6Suzuki T,Funada M,Sugano Y,et al.Effects of a lipopolysaccharide from Pantoea agglomerans on the cocaine-induced place preference[J]. Life Sci, 1994, 54(6): 175-180.
-
7Kamei J, Iwamoto Y, Suzuki T, et al. Antinociceptive effect of lipopolysaccharide from Pantoea agglomerans on streptozotocin-induced diabetic mice[J].Eur J Pharmacol, 1994, 251 (1): 95-98.
-
8Goto S, Sakai S, Kera J, et al. Intradermal administration of lipopolysaccharide in treatment of human cancer[J]. Cancer Immunol Immunother, 1996, 42(4): 255-261.
-
9梁自乾,李德绘,韦俊,蔡捷,冷静,郭松超,叶峻,松源一郎.LPSP霜剂在烧伤创面的应用[J].广西医科大学学报,2000,17(1):16-17. 被引量:3
-
10黄志明,黄仁彬,陈家欢,陈美芳,杨斌,黎肇炎,王乃平.小麦非致病菌脂多糖对小鼠免疫功能的影响[J].广西医科大学学报,2002,19(2):195-197. 被引量:4
-
1朱峰,郭光华.BMSCs在急性肺损伤中的研究进展[J].中国修复重建外科杂志,2011,25(2):198-201. 被引量:3
-
2雷俊霞,王贞,惠大阳,余伟华,夏文杰,陈纯,张群周,Ann D Le,付涌水,项鹏.骨髓间质干细胞上TLR2和TLR4激活对其免疫调节效应的不同影响[J].中国病理生理杂志,2010,26(A10):2030-2030.
-
3张万会,朱运龙.P物质的免疫调节效应[J].生理科学进展,1992,23(2):116-121. 被引量:21
-
4左冬梅,寿折星,范恒,刘星星,曹丹,邹舟.间充质干细胞与炎症性肠病的研究进展[J].胃肠病学,2013,18(3):182-184. 被引量:1
-
5焦国慧,杨荣存.Th17细胞的分化调节[J].中国免疫学杂志,2009,25(1):89-94. 被引量:3
-
6刘英杰,王继春,郑伟,朱晓彤,曹雅明.IL-10在约氏疟原虫感染过程中免疫调节作用的实验观察[J].中国病原生物学杂志,2007,2(1):29-31. 被引量:1
-
7孟艳燕,王秀杰,田广伟,刘英杰.CD4^+CD25^+调节性T细胞在疟疾感染中的免疫调节作用[J].日本医学介绍,2007,28(9):427-429. 被引量:1
-
8杨巍,王宇峰,蒋颖超,杨林,常雅萍.流感疫苗诱导Hela细胞凋亡与免疫调节效应[J].中国生物制品学杂志,2007,20(7):486-488.
-
9徐姗,姚咏明,盛志勇.树突细胞与T淋巴细胞相互作用及其免疫调节效应[J].解放军医学杂志,2006,31(9):919-921. 被引量:2
-
10付豆,丁国华,王惠明.间充质干细胞及其在肾脏疾病中的作用研究进展[J].国际泌尿系统杂志,2016,36(6):938-942.