期刊文献+

软药设计在新药开发中的应用

下载PDF
导出
作者 李坤 杜玉民
出处 《河北医科大学学报》 CAS 2005年第3期230-231,共2页 Journal of Hebei Medical University
  • 相关文献

参考文献8

  • 1赵冬梅,李燕,卢业竑.药物代谢研究在新药开发中的作用[J].药学学报,2000,35(2):156-160. 被引量:23
  • 2Bodor N, Buchwald P. Soft durg design: general principle and recent applications[J]. Medical Research Review, 2000,20(1):58-101.
  • 3Buchwald P, Bodor N. Structure-based estimation of enzymatic hydrolysis rates and its application computer-aided retrometabolic drug design[J]. Pharmazie Die, 2000,55(3):210-217.
  • 4Calvani M, Critelli L, Gallo G, et al. L-Carnitine esters as soft, broad-spectrum antimicrobial amphiphiles[J]. J Med Chem, 1998,41(13):2227-2233.
  • 5Raatikainen MJP, Napolitano CA, Druzgala P, et al. Electrophysiological effects of a novel, short-acting and potent ester derivative of amiodarone, ATI-2001, in guinea pig isolated heart[J]. J Pharmacol Exp Ther, 1996,277(3):1454-1463.
  • 6Little RJ, Bodor N, loftson T. Soft drugs based on hydrocortisone: the inactive metabolite approach and its application to steroidal antiinflammatory agents[J]. Pharmaceutical Research, 1999,16(6):961-967.
  • 7Kitamura A, Sakamoto A, Inoue T, et al. Efficacy of an ultra-short-acting adrenoreceptor blocker (ONO-1101) in attenuating cardiovascular responses to endotracheal intubation[J]. Eur J Clin Pharmacol, 1997,51(6):467-471.
  • 8Bodor N, Buchwald P, Huang MJ. Computer- assisted design of new drugs based on retrometabolic concepts[J]. SAR QSAR Environ Res, 1998,8(1-2):41-92.

二级参考文献4

  • 1Lin J H,Clin Pharmacokinet,1998年,35卷,361页
  • 2Lin J H,Pharmacol Rev,1997年,49卷,403页
  • 3Yasumori T,J Pharmacol Exp Ther,1993年,264卷,89页
  • 4Lin J H,Drug Metab Dispos,1991年,19卷,9页

共引文献22

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部