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促红细胞生成素防治极低出生体重儿贫血16例

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摘要 34例极低出生体重儿随机分为治疗组(16例)和对照组(18例),均于出生第4天起口服葡萄糖酸亚铁糖浆(按元素铁9mg·kg-1·d-1计算)、维生素C0.2g/d、维生素E15mg/d。治疗组在上述治疗的基础上加用重组人类促红细胞生成素(rh EPO),每周600IU/kg,分3次皮下注射,疗程6周。结果示治疗组治疗后网织红细胞计数较对照组明显升高(P<0.01);两组血红蛋白及红细胞压积均于出生后逐渐下降,但治疗组下降缓慢,在治疗后第1、3、5、7周相比差异均有统计学意义(P<0.01);治疗组疗程结束后存在贫血者4例(25.0%),明显低于对照组13例(72.2%),P<0.01;治疗组输血2例,而对照组输血11例。提示rh EPO加铁剂能有效防治极低出生体重儿贫血。
出处 《中华全科医师杂志》 2005年第5期303-304,共2页 Chinese Journal of General Practitioners
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