间苯二甲酸双羟乙酯-5-磺酸钠的合成研究

Study on the Synthesis of 5-Sodium Sulfo Bis-(hydroxyethyl) Isophthalate

采用间苯二甲酸二甲酯 5 磺酸钠(SIPM )和乙二醇(EG)为原料,在一定的温度和催化剂条件下进行酯交换反应制备间苯二甲酸双羟乙酯 5 磺酸钠(SIPE)。用高效液相色谱(HPLC)法测定酯交换率,系统研究了催化剂、EG

5-Sodium sulfo bis-(hydroxyethyl) isophthalate(SIPE) was synthesized by the transesterification of 5-sodium sulfoisophthalic acid dimethyl ester (SIPM) with ethylene glycol(EG) in the presence of catalyst at certain temperature. The ester exchanging rate was determined by HPLC. The effects of catalysts, the ratio of EG/SIPM and reaction time on the ester exchanging rate of SIPE were studied.