太原市不同人群SARS血清流行病学调查

Seroepidemiological study on severe respiratory syndrome among different population in Taiyuan

目的 分析山西省太原市严重急性呼吸系统综合征(SARS)患者及其密切接触者和社区人群中血清SARS抗体水平。方法 采用ELISA方法检测3组人群的SARS特异性抗体,并进行分析比较。结果 SARS患者、密切接触者和社区健康人群的SARS冠状病毒(SARS -CoV)抗体阳性率分别为5 2 0 8% ,4 6 3%和1.88% ,3组人群比较差异有统计学意义;3组人群中不同年龄组及性别间抗体阳性率差异无统计学意义。在密切接触者既往各类接触史中,除“接触时有无洗手”与血清SARS -CoV抗体阳性有关外,未发现其它有关因素。结论 太原SARS病例存在过度诊断现象,密切接触者和普通人群中可能存在SARS的隐性感染。

Objective To analyze the SARS-CoV antibody level among pa tients with severe acute respiratory syndrome (SARS),close contactors with suspe cted SARS and community-based population in Taiyuan,Shanxi Province. Methods ELISA method was used to detect the SARS-CoV anti body level among patients with severe acute respiratory syndrome (SARS),close co ntactor with SARS and community-based population followed a comparative analysis .Results Positive rate of SARS patients,close contactor an d general population was 52.08%,4.63% and 1.88% respectively.No difference rate of SARS-CoV Ab was found between male and female and among difference age groups .No relationship was found between SARS-CoV Ab and history of contacting factors except the item “washing hands after contacting suspected SARS patients”. Conclusion Over SARS diagnosis existed during SARS ep idemic period in Taiyuan.Latent infection of SARS maybe existed in SARS cl ose contactor and community-based population.